NIH Weekly Funding Opportunities and Policy Notices
Notice NOT-DK-24-020 from the NIH Guide for Grants and Contracts
Notice NOT-OD-24-130 from the NIH Guide for Grants and Contracts
Notice NOT-OD-24-128 from the NIH Guide for Grants and Contracts
Notice NOT-HS-24-016 from the NIH Guide for Grants and Contracts
Notice NOT-TW-24-007 from the NIH Guide for Grants and Contracts
Funding Opportunity PAR-24-234 from the NIH Guide for Grants and Contracts. Advances in structural biology have enabled the characterization of large protein assemblies that are linked to AD/ADRD pathology. However, most structural biology approaches require purified samples from cells and tissues or use recombinant bacterial proteins. The derived structures using ex-vivo material may not report the diversity of physiologically relevant species because reconstruction relies on class averaging that is biased towards dominant conformations that survive methodological processing. Recent developments in structural biology offer the possibility of in situ characterization of specific macromolecular assemblies. Structural information of protein assemblies and aggregates in their native cellular and tissue environments could facilitate rational structure-based ligand development. Currently, PET ligands that specifically identify and monitor the accumulation of aggregated and misfolded proteins in AD/ADRD patients are lacking.
Notice NOT-EY-24-010 from the NIH Guide for Grants and Contracts
Notice NOT-GM-24-040 from the NIH Guide for Grants and Contracts
Funding Opportunity PAR-24-199 from the NIH Guide for Grants and Contracts. The purpose of this notice of funding opportunity (NOFO) is to enhance the participation of individuals from nationally underrepresented backgrounds to enhance the participation of individuals from nationally underrepresented backgrounds in cardiovascular, pulmonary, hematologic and sleep disorders research across the career development continuum by providing support to institutions that promote diversity. The NHLBI's T32 Training Program for Institutions That Promote Diversity is a Ruth L. Kirschstein National Research Service Award Program intended to support training of predoctoral and health professional students and individuals in postdoctoral training institutions with an institutional mission focused on serving health disparity populations not well represented in scientific research, or institutions that have been identified by federal legislation as having an institutional mission focused on these populations, with the potential to develop meritorious training programs in cardiovascular, pulmonary, and hematologic diseases, and sleep disorders. These institutions are uniquely positioned to engage minority and other health disparity populations in research, translation, and implementation of research advances that impact health outcomes, as well as provide health care for these populations. This NOFO does not allow appointed trainees to lead an independent clinical trial but does allow them to obtain research experience in a clinical trial led by a mentor or co-mentor.
Notice NOT-NS-24-081 from the NIH Guide for Grants and Contracts
Funding Opportunity RFA-DK-25-012 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity (NOFO) is a non-competitive funding opportunity intended to fund a single award. The NIDDK is announcing its intent to issue a single source cooperative agreement to the University of Pennsylvania to continue the mission of the existing Human Pancreas Analysis Program for Type 1 Diabetes (HPAP-T1D). This NOFO will support one team of investigators with combined expertise in human pancreas physiology and pathophysiology; immunology and autoimmunity; collection, processing and multimodal analysis of human pancreatic tissues and immune compartments; and biological database building, curation and management, that will be tasked to: 1) identify, collect and intensively characterize primary pancreatic tissues and immune cells from patients with type 1 diabetes (T1D) or at risk of developing the disease, as well as age-matched controls; and 2) analyze, organize and share the data resulting from the study of these tissues through the existing PANC DB open-access resource database. HPAP-T1D is a component of the Human Islet Research Network or HIRN. HIRN was created in 2014 to support innovative and collaborative translational research to understand how human beta cells are lost in T1D, and to find innovative strategies to protect and replace functional human beta cell mass.
Notice NOT-AG-24-023 from the NIH Guide for Grants and Contracts
Notice NOT-CA-24-059 from the NIH Guide for Grants and Contracts
Notice NOT-GM-24-034 from the NIH Guide for Grants and Contracts
Notice NOT-MD-24-017 from the NIH Guide for Grants and Contracts
Notice NOT-MH-24-345 from the NIH Guide for Grants and Contracts
Notice NOT-DC-24-031 from the NIH Guide for Grants and Contracts
Notice NOT-DC-24-030 from the NIH Guide for Grants and Contracts
Notice NOT-PM-24-003 from the NIH Guide for Grants and Contracts
Funding Opportunity RFA-AT-24-009 from the NIH Guide for Grants and Contracts. This notice of funding opportunity (NOFO) invites applications for REsearch Across Complementary and Integrative Health Institutions (REACH) virtual resource centers. REACH virtual resource centers will foster institutional partnerships and provide resources to support research activities and research training for faculty who work at accredited complementary and integrative health clinical institutions, such as: Schools of acupuncture, chiropractic, osteopathy, naturopathy, physical therapy, and music and art therapy. The REACH virtual resource centers will provide a variety of services and resources including, but not limited to Administrative Support, Research Support, Grantsmanship, Mentoring and Training, and Team Building to support clinician scientists located at complementary and integrative health clinical institutions to form multi and interdisciplinary research teams and pursue externally funded research aligned with NCCIH Strategic Priorities for symptom management. REACH centers should focus on resources to support investigators pursuing clinical research (e.g., observational, epidemiological, mechanistic clinical research, mixed methods, feasibility studies, etc). It is expected that REACH virtual resource centers will (1) improve the quality and quantity of federal research grant applications submitted by clinician scientist faculty at complementary and integrative health clinical institutions; (2) aid the formation of multi and interdisciplinary research partnerships across partnering complementary and integrative health clinical institutions; (3) help to enhance the research environment at complementary and integrative health clinical institutions; and (4) support a pipeline for clinician scientists trained in complementary and integrative health practices to pursue research careers at clinical institutions.