NIH Weekly Funding Opportunities and Policy Notices
Funding Opportunity PAR-17-163 from the NIH Guide for Grants and Contracts. Patients with many disabilities report problems sleeping, but specific sleep disorders are often not diagnosed. Because sleep affects many physiological and behavioral parameters--depression, anxiety, pain, cancer, cardiovascular changes, immune function-- sleep disorders should be diagnosed and appropriately treated to maximize benefit of rehabilitation. Research is needed on ways to best approach this complexity in the context of medical rehabilitation for a primary, non-sleep disorder.
Notice NOT-TR-17-009 from the NIH Guide for Grants and Contracts
Funding Opportunity RFA-TR-17-007 from the NIH Guide for Grants and Contracts. The goal of this Funding Opportunity Announcement (FOA) is to enable the development of 3D-bioprinted tissue models for drug discovery, including efficacy studies and toxicology research through a collaborative arrangement between the 3-D Bioprinting Program at the National Center for Advancing Translational Sciences (NCATS) and extramural scientists. NCATS intramural scientists will provide expertise for 3-D bioprinting, assay development and drug screening stages of the projects. Extramural investigators will provide appropriate cell resources, disease expertise and model validation in collaboration with NCATS to perform drug screening of bioprinted materials. The research application will involve 3-D bioprinting in a screening format of patient-derived cells supplied by the extramural investigators, characterization and validation of bioprinted materials by NCATS investigators and extramural collaborators, and screening of appropriate molecular libraries.
Funding Opportunity RFA-RM-17-004 from the NIH Guide for Grants and Contracts. The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching goal of this Common Fund R25 program is to support educational activities that complement and/or enhance the training of a workforce to meet the nations biomedical, behavioral and clinical research needs. To accomplish the stated over-arching goal, this FOA will support creative educational activities with a primary focus on Curriculum or Methods Development in cryoelectron microscopy (cryoEM) for structural biology research.
Funding Opportunity PAR-17-149 from the NIH Guide for Grants and Contracts. Understanding the mechanisms by which complementary or integrative Mind and Body Interventions exert their clinical effects is critical for the development of optimized interventions that target specific conditions and disorders.
Notice NOT-NS-17-017 from the NIH Guide for Grants and Contracts
Notice NOT-CA-17-028 from the NIH Guide for Grants and Contracts
Notice NOT-TR-17-010 from the NIH Guide for Grants and Contracts
Funding Opportunity PAR-17-160 from the NIH Guide for Grants and Contracts. The National Institute of General Medical Sciences (NIGMS) invites applications for Institutional Development Award (IDeA) Networks of Biomedical Research Excellence (INBRE) awards from investigators at biomedical research institutions that award doctoral degrees in the health sciences or sciences related to health or at independent biomedical research institutes with ongoing biomedical research programs funded by the NIH or other Federal agencies within the IDeA eligible states. The purpose of the INBRE program is to augment and strengthen the biomedical research capacity of an IDeA-eligible state. The INBRE program represents a collaborative effort to sponsor research between research intensive institutions and institutes, primarily undergraduate institutions, community colleges, and Tribally Controlled Colleges and Universities (TCCUs), as appropriate.
Funding Opportunity PAR-17-161 from the NIH Guide for Grants and Contracts. The National Center for Medical Rehabilitation Research (NCMRR) Early Career Research (ECR) Award (R03) is intended to support both basic and clinical research from rehabilitation scientists who are establishing independent research careers. It cannot be used to support thesis/dissertation research or research conducted by postdoctoral fellows. The research should be focused on one or more of the areas within the biomedical and behavioral mission of NCMRR: pathophysiology and management of chronically injured nervous and musculoskeletal systems; repair and recovery of motor and cognitive function; functional plasticity, adaptation, and windows of opportunity for rehabilitation interventions; rehabilitative strategies involving pharmaceutical, stimulation, neuroengineering approaches, exercise, motor training, and behavioral modifications; pediatric rehabilitation; secondary conditions associated with chronic disabilities; improved diagnosis, assessment, and outcome measures; and development of orthotics, prosthetics, and other assistive technologies and devices. The NCMRR ECR Award supports different types of projects including secondary analysis of existing data; small, self-contained research projects; development of research methodology; translational research; outcomes research; and development of new technology. Irrespective of the type of project, the intent of the NCMRR ECR Award is for the Program Director(s)/Principal Investigator(s) (PD(s)/PI(s)) to obtain sufficient preliminary data for a subsequent R01 application.
Funding Opportunity PAR-17-162 from the NIH Guide for Grants and Contracts. Understanding the mechanisms by which complementary or integrative Mind and Body Interventions exert their clinical effects is critical for the development of optimized interventions that target specific conditions and disorders.
Notice NOT-DK-17-010 from the NIH Guide for Grants and Contracts
Funding Opportunity PAR-17-159 from the NIH Guide for Grants and Contracts. The National Library of Medicine seeks applications for novel informatics and data science approaches that can help individuals gather, manage and use data and information about their personal health. A goal of this program is to advance research and application by patients and the research community through broadly sharing the results via publication, and through open source mechanisms for data or resource sharing.
Funding Opportunity RFA-AI-17-001 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to support studies to evaluate candidate cellular therapies to treat radiation-induced injuries in appropriate in vivo models when administered 24 hours or more post-irradiation. The research should be aimed toward the eventual approval of candidate cellular therapies under the United States Food and Drug Administration (FDA) Animal Rule licensure pathway.
Funding Opportunity PA-17-157 from the NIH Guide for Grants and Contracts. Genetic and genomic studies have identified genes and gene variants that may impact the fundamental biological mechanisms underpinning substance use disorders (SUDs). Discovery of these genes/variants, while extremely valuable, is only the first step in understanding the molecular processes that influence SUDs. This Funding Opportunity Announcement (FOA) encourages basic functional genetic and genomic research in two areas: 1. functional validation to determine which candidate genes/variants/epigenetic/non-coding RNA features have an authentic role in SUDs, and 2. detailed elucidation of the molecular pathways and processes modulated by candidate genes/variants, particularly for those genes with an unanticipated role in SUDs.
Funding Opportunity PA-17-155 from the NIH Guide for Grants and Contracts. Genetic and genomic studies have identified genes and gene variants that may impact the fundamental biological mechanisms underpinning substance use disorders (SUDs). Discovery of these genes/variants, while extremely valuable, is only the first step in understanding the molecular processes that influence SUDs. This Funding Opportunity Announcement (FOA) encourages basic functional genetic and genomic research in two areas: 1. functional validation to determine which candidate genes/variants/epigenetic/non-coding RNA features have an authentic role in SUDs, and 2. detailed elucidation of the molecular pathways and processes modulated by candidate genes/variants, particularly for those genes with an unanticipated role in SUDs.
Funding Opportunity PAR-17-156 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to accelerate research evaluating electronic cigarettes (e-cigarettes, electronic nicotine delivery systems, ENDS) as a potential means of reducing the risks associated with combustible tobacco use. This goal will be achieved by funding clinical studies that use the newly-developed NIDA Standard Research E-cigarette (SREC) to examine potential risks and benefits associated with e-cigarette use in current tobacco smokers. Ultimately, this FOA aims to evaluate whether e-cigarettes can reduce the risks associated with combustible tobacco use and to establish the NIDA SREC as a standard to which other e-cigarettes can be compared. Studies submitted to this FOA should examine the effects of the SREC on multiple behavioral and health biomarkers in current tobacco smokers and may include examination of whether e-cigarettes can reduce the negative health impacts of conventional tobacco use, and / or examine their effects on craving and dependence. Funding will be contingent upon the FDA Center for Tobacco Products (CTP) determination that the studies fall under their regulatory jurisdiction. Furthermore, funding will require that CTP accepts the use of the NIDA SREC as an Investigational Tobacco Product (ITP) in the proposed study, or determines that an ITP is not required. Studies funded by this FOA are expected to rapidly increase understanding of whether e-cigarettes reduce the risks associated with tobacco use. Additionally, these studies may provide significant data to inform e-cigarette public health policy decision-making.
Funding Opportunity PAR-17-158 from the NIH Guide for Grants and Contracts. This FOA seeks applications which propose secondary analyses of existing clinical research datasets to investigate constructs identified in the NIMH's Research Domain Criteria (RDoC) initiative and to test novel hypotheses using the RDoC framework.
Funding Opportunity RFA-FD-17-004 from the NIH Guide for Grants and Contracts. This program expansion FOA provides a mechanism for organizations receiving only competition A funding under PAR-16-137 to apply for competition B funding. Only those states/territories currently receiving funding for competition A under PAR-16-137 are eligible to apply.
Notice NOT-AG-17-004 from the NIH Guide for Grants and Contracts