NIH Weekly Funding Opportunities and Policy Notices
Notice NOT-OD-17-028 from the NIH Guide for Grants and Contracts
Notice NOT-OD-17-029 from the NIH Guide for Grants and Contracts
Notice NOT-DE-17-006 from the NIH Guide for Grants and Contracts
Funding Opportunity PAR-17-093 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to stimulate translation of scientific discoveries and engineering developments in imaging or spectroscopic technologies into methods or tools that address problems in cancer biology, risk of cancer development, diagnosis, treatment, and/or disease status. A distinguishing feature of each application will be formation of an academic-industrial partnership, which is a strategic alliance of investigators in academic, industrial, and any other entities who work together as partners to identify and translate a technological solution or mitigation of a cancer-related problem.
Funding Opportunity PA-17-091 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is to support research that explores the premise that fertility status can be a marker for overall health. It is clear that chronic conditions such as cancer, diabetes, and obesity can impair fertility, however less is known about the extent to which fertility status can impact or act as a marker for overall health. Data suggest that infertility is not necessarily a unique disease of the reproductive axis, but is often physiologically or genetically linked with other diseases and conditions. Recent epidemiologic studies demonstrate links between fertility status in both males and females and various somatic diseases and disorders. Taken together, these data strongly suggest that fertility status can be a window into overall health. This FOA focuses on studies evaluating fertility as a marker for overall health and therefore applications that look at the effects of a disease or disorder on fertility are outside the scope of this program.
Funding Opportunity PA-17-092 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is to support exploratory/developmental research that explores the premise that fertility status can be a marker for overall health. It is clear that chronic conditions such as cancer, diabetes, and obesity can impair fertility, however less is known about the extent to which fertility status can impact or act as a marker for overall health. Data suggest that infertility is not necessarily a unique disease of the reproductive axis, but is often physiologically or genetically linked with other diseases and conditions. Recent epidemiologic studies demonstrate links between fertility status in both males and females and various somatic diseases and disorders. Taken together, these data strongly suggest that fertility status can be a window into overall health. This FOA focuses on studies evaluating fertility as a marker for overall health and therefore applications that look at the effects of a disease or disorder on fertility are outside the scope of this program.
Funding Opportunity RFA-ES-16-009 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to invite applications for multi-component projects that will investigate the impact of climate change on emerging public health threats associated with marine and Great Lakes Basin environments. The focus of the program will be to support research on the exposures, toxicities and human health impacts that arise in these environments and how climate change is influencing these factors now and in the future. The FOA solicits applications that will achieve program goals through integrated, multidisciplinary scientific approaches and a community engagement component.
Notice NOT-DK-17-006 from the NIH Guide for Grants and Contracts
Notice NOT-HL-16-480 from the NIH Guide for Grants and Contracts
Notice NOT-TR-17-008 from the NIH Guide for Grants and Contracts
Notice NOT-OD-17-027 from the NIH Guide for Grants and Contracts
Funding Opportunity RFA-CA-17-005 from the NIH Guide for Grants and Contracts. This National Cancer Institute (NCI) funding opportunity announcement (FOA) solicits applications for multidisciplinary Cancer Immune Monitoring and Analysis Centers (CIMACs) that will serve as the main units of the Network for correlative studies in clinical trials involving immunotherapy. The Network will encompass two to three CIMACs (to be supported by this FOA) and a single Cancer Immunologic Data Commons (CIDC) (to be supported by the companion FOA, RFA-CA-17-006) forming a CIMACs-CIDC Network.
Funding Opportunity RFA-CA-17-006 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is to solicit applications for establishment of a Cancer Immunologic Data Commons (CIDC) to provide bioinformatics support as part of a Network for correlative studies in clinical trials involving cancer immunotherapy. The Network will encompass a single CIDC award (to be supported by this FOA) and up to three Cancer Immune Monitoring and Analysis Centers (CIMACs) (to be supported by a companion FOA, RFA-CA-17-005).
Funding Opportunity RFA-CA-17-001 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) will support canine clinical studies using immunotherapeutic agents and novel drug combinations (such as immune modulators, molecular targeted agents, chemotherapy, and/or radiation) together with laboratory correlative studies that seek to describe characterize and understand the cellular and molecular mechanisms that determine the anti-tumor response (or non-response) in dogs with spontaneous tumors. The FOA will support a network of laboratories and canine clinical trial sites. A companion funding opportunity (see U24 funding opportunity RFA-CA-17-002) will support a coordinating center that will aid in the development, standardization, and conduct of the clinical and laboratory studies as well as data management across the funded U01 sites.
Funding Opportunity RFA-CA-17-002 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) will support a coordinating center for a network of cooperative agreements (see U01 FOA RFA-CA-17-001) that will conduct clinical trials in pet dogs with spontaneous tumors and perform laboratory correlative studies associated with the clinical trials. This FOA will work with the NCI Comparative Oncology Program (COP) of the NCI's Center for Cancer Research as an integral component and will provide statistical support; assist with the development and standardization of clinical protocols and laboratory immune monitoring assays; assist with the implementation of clinical studies in immunotherapy and combination agents including accrual to the trials; manage clinical and correlative data from all U01 sites and their collaborators including immune-related adverse events; facilitate the sharing of agents, specimens, and data; and create an ad hoc steering committee of required expertise--both inside and outside the U01 network, including the PD/PIs of the U01s, representatives of the COP and the NCI Program Official--to ensure that the goals of the network are accomplished.
Funding Opportunity RFA-CA-17-015 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is to stimulate research in the area of PDAC microenvironment with the ultimate goal of understanding the interaction between tumors and the microenvironment. The plan is to design new immunotherapy and combination interventions that would accommodate and build on the distinct characteristics of this interaction. It is expected that the interventions will lead to improved responses in pre-clinical models and clinical evaluation either in NCI-based early phase networks (ETCTN), or by industry or cancer centers.
Funding Opportunity RFA-CA-17-016 from the NIH Guide for Grants and Contracts. This funding opportunity announcement (FOA) invites applications to establish a Resource Center (RC) for the Consortium for Pancreatic Ductal Adenocarcinoma (PDAC) Translational Studies on the Tumor Microenvironment (Consortium) that has the ultimate goal to design new immunotherapy and combination interventions in PDAC.
Funding Opportunity PA-17-089 from the NIH Guide for Grants and Contracts. This funding opportunity announcement (FOA) invites studies employing secondary analysis of existing cohorts, data sets and biorepositories to explore clinically related issues on aging changes influencing health across the lifespan, including diseases and disabilities in older persons. Use of cohorts that are linked to electronic health record systems and/or Centers for Medicare and Medicaid Services (CMS) administrative data are especially welcome. This FOA will support exploratory analysis of innovative hypotheses in clinical aging research and/or to inform design of future epidemiologic or human intervention studies. Costs related to data harmonization, archival activities and/or assay refinement may be included in the budget, as long as they are pertinent to the specific aims of the proposed project.
Funding Opportunity PA-17-088 from the NIH Guide for Grants and Contracts. This funding opportunity announcement (FOA) invites applications employing secondary analysis of existing data sets or stored biospecimens, to address clinically related issues on aging changes influencing health across the lifespan, and/or on diseases and disabilities in older persons. Use of cohorts that are linked to electronic health record systems and/or Centers for Medicare and Medicaid Services (CMS) administrative data are especially welcome. This FOA will support activities addressing specific hypotheses in clinical aging research and/or to inform the design and implementation of future epidemiologic or human intervention studies, or current geriatric practice in maintenance of health, management of disease, and prevention of disability. Existing data sets may also be used to develop and test new statistical analytical approaches. Costs for archiving of data to be made publicly available and those associated with data harmonization or assay refinement/validation may be included in the budget, as long as these activities are pertinent to the proposed secondary analyses.
Funding Opportunity PA-17-090 from the NIH Guide for Grants and Contracts. The National Library of Medicine, in conjunction with NIH Institutes and Centers (ICs) named above, announces an Administrative Supplement opportunity available to eligible NIH awardees with active R01 grants and, in some cases, with the other active awards with the activity codes listed above. (see IC-specific details in the Activity Code section above).