NIH Weekly Funding Opportunities and Policy Notices
Notice NOT-AT-17-002 from the NIH Guide for Grants and Contracts
Notice NOT-OD-17-033 from the NIH Guide for Grants and Contracts
Notice NOT-CA-17-017 from the NIH Guide for Grants and Contracts
Notice NOT-DK-17-008 from the NIH Guide for Grants and Contracts
Notice NOT-OD-17-034 from the NIH Guide for Grants and Contracts
Funding Opportunity PA-17-119 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages applications from investigators that propose to study the developing brain or brain areas that play significant roles in mediating emotional and motivated behavior and in substance use and dependence. All stages of brain development are of interest, but a new emphasis of the current reissue of this initiative is to support basic neuroscience research on fundamental mechanisms of brain development during prepuberty and the adolescent period in relation to the problems of substance abuse and co-morbidity with psychiatric disorders. Topics of interest pertaining to brain development of this initiative include, but are not limited to, the euphoric properties of abused substances, actions of psychotherapeutic agents, and their consequences on memory, cognitive and emotional processes. A major goal of this initiative is to understand how exposure to substances of abuse and environmental insults affects the cellular and molecular mechanisms underlying nervous system development and neural circuit functions implicated in substance use and addiction.
Discovering Novel Targets: The Molecular Genetics of Drug Addiction and Related Co-Morbidities (R01)
Funding Opportunity PA-17-120 from the NIH Guide for Grants and Contracts. This FOA encourages applications for research projects that identify, validate and/or functionally characterize loci, genetic variations and haplotypes that are associated with vulnerability to addiction and that potentially inform the likelihood of responsiveness to treatment. Applications that propose to examine intermediate phenotypes or endophenotypes to assess the molecular genetics of drug addiction, addiction vulnerability and/or their associated co-morbidities and how they are related to drug addiction are especially encouraged. Also encouraged are genetic as well as computational and large-scale genomic approaches, which may include but are not limited to linkage, linkage disequilibrium, case-control or family-based studies, and integration of data from other databases that may supplement substance abuse genetics and genomics data. Data may be collected from the general population, special populations, recent admixed populations, and/or animal models. Secondary data analysis of data collected from the general population, special populations, recent admixed populations, and/or animal models is also appropriate for this announcement. Investigators are encouraged to include functional characterization, gene x gene interactions, gene x environment interactions, gene x environment x development interactions, pharmacogenetics, and non-human models, as appropriate.
Funding Opportunity PAR-17-122 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to encourage grant applications for investigator-initiated exploratory clinical trials to the National Institute of Neurological Disorders and Stroke (NINDS). The trials must address questions within the mission and research interests of the NINDS and may evaluate drugs, biologics, and devices, as well as surgical, behavioral and rehabilitation therapies. Information about the mission and research interests of the NINDS can be found at the NINDS website (http://www.ninds.nih.gov/)
Notice NOT-HL-16-482 from the NIH Guide for Grants and Contracts
Funding Opportunity PA-17-106 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) solicits innovative, targeted basic behavioral and social science and intervention development research to reduce incident HIV infections and improve the health of those living with HIV. This FOA encourages research designed to (a) conduct basic behavioral and social science research that is needed to advance the development of HIV prevention and care interventions, (b) translate and operationalize the findings from these basic studies to develop interventions and assess their acceptability and feasibility and (c) conduct tests of the efficacy of HIV prevention and care interventions. This FOA uses the R01 grant mechanism while PA-17-105 uses the R21 mechanism.
Funding Opportunity PA-17-105 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages innovative, targeted basic behavioral and social science and intervention development research to reduce incident HIV infections and improve the health of those living with HIV. This FOA encourages research designed to (a) conduct basic behavioral and social science research that is needed to advance the development of HIV prevention and care interventions, (b) translate and operationalize the findings from these basic studies to develop interventions and assess their acceptability and feasibility and (c) conduct tests of the efficacy of HIV prevention and care interventions. PA-17-106 uses the R01 grant mechanism while this FOA uses the R21 mechanism. High risk/high payoff projects that lack preliminary data or utilize existing data may be most appropriate for the R21 mechanism, while applicants with preliminary data and/or include longitudinal analysis may wish to apply using the R01 mechanism.
Funding Opportunity PA-17-116 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to encourage exploratory/developmental research to improve self-management and quality of life in children and adolescents with chronic conditions. Managing a chronic condition is an unremitting responsibility for children and their families. Children with a chronic condition and their families have a long-term responsibility for self-management. This FOA encourages research that takes into consideration various factors that influence self-management such as individual differences, biological and psychological factors, family/caregivers and sociocultural context, family-community dynamics, healthcare system factors, technological advances, and the role of the environment.
Funding Opportunity PA-17-115 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to encourage research to improve self-management and quality of life in children and adolescents with chronic conditions. Managing a chronic condition is an unremitting responsibility for children and their families. Children with a chronic condition and their families have a long-term responsibility for self-management. This FOA encourages research that takes into consideration various factors that influence self-management such as individual differences, biological and psychological factors, family/caregivers and sociocultural context, family-community dynamics, healthcare system factors, technological advances, and the role of the environment.
Funding Opportunity PAR-17-107 from the NIH Guide for Grants and Contracts. The purpose of this Small Business Technology Transfer Research (STTR) FOA is to encourage small businesses and their research partners to develop assistive robotics and related technology that would enhance health and reduce illness and disability in older Americans suffering from Alzheimer's Disease (AD), AD-related dementias (ADRD), and other comorbidities. In addition, this FOA encourages small businesses and their research partners to develop assistive robotics addressing the needs and conditions of caregivers to older Americans suffering from AD and ADRD.
Funding Opportunity PAR-17-108 from the NIH Guide for Grants and Contracts. The purpose of this Small Business Innovation Research (SBIR) FOA is to encourage small businesses to develop assistive robotics and related technology that would enhance health and reduce illness and disability in older Americans suffering from Alzheimer's Disease (AD), AD-related dementias (ADRD), and other comorbidities. In addition, this FOA encourages small businesses to develop assistive robotics addressing the needs and conditions of caregivers to older Americans suffering from AD and ADRD.
Funding Opportunity PA-17-117 from the NIH Guide for Grants and Contracts. This initiative encourages research that targets the reduction of health disparities among children. Investing in early childhood development is essential. Specific targeted areas of research include bio-behavioral studies that incorporate multiple factors that influence child health disparities such as biological (e.g., genetics, cellular, organ systems), lifestyle factors, environmental (e.g., physical and family environments) social (e.g., peers), economic, institutional, and cultural and family influences; studies that target the specific health promotion needs of children with a known health condition and/or disability; and studies that test, evaluate, translate, and disseminate health promotion prevention and interventions conducted in traditional and non -traditional settings
Funding Opportunity PA-17-118 from the NIH Guide for Grants and Contracts. This initiative encourages research that targets the reduction of health disparities among children. Investing in early childhood development is essential. Specific targeted areas of research include bio-behavioral studies that incorporate multiple factors that influence child health disparities such as biological (e.g., genetics, cellular, organ systems), lifestyle factors, environmental (e.g., physical and family environments) social (e.g., peers), economic, institutional, and cultural and family influences; studies that target the specific health promotion needs of children with a known health condition and/or disability; and studies that test, evaluate, translate, and disseminate health promotion prevention and interventions conducted in traditional and non -traditional settings.
Funding Opportunity PA-17-112 from the NIH Guide for Grants and Contracts. Long-term misuse and chronic exposure to abused substances can produce widespread changes in brain structure and function. Although much progress has been made, additional research is still needed to identify the neurobiological changes that result from substance use, and how these changes contribute to substance use disorders. The overarching goals of the research areas described in this FOA are to understand the neurobiological mechanisms underlying substance use disorders, with special emphasis on identifying changes and neuroadaptations that occur during dependence, withdrawal, and relapse to chronic substance use. An understanding of the basic mechanisms underlying substance use disorders can help to identify targets for prevention and treatment interventions. Research utilizing basic, translational, or clinical approaches is appropriate.
Funding Opportunity PA-17-111 from the NIH Guide for Grants and Contracts. Long-term misuse and chronic exposure to abused substances can produce widespread changes in brain structure and function. Although much progress has been made, additional research is still needed to identify the neurobiological changes that result from substance use, and how these changes contribute to substance use disorders. The overarching goals of the research areas described in this FOA are to understand the neurobiological mechanisms underlying substance use disorders, with special emphasis on identifying changes and neuroadaptations that occur during dependence, withdrawal, and relapse to chronic substance use. An understanding of the basic mechanisms underlying substance use disorders can help to identify targets for prevention and treatment interventions. Research utilizing basic, translational, or clinical approaches is appropriate.
Funding Opportunity PAR-17-121 from the NIH Guide for Grants and Contracts. NIDA Core Center of Excellence Grants (P30) are intended to bring together investigators currently funded by NIH or other Federal or non-Federal sources, to enhance the effectiveness of existing research and also to extend the focus of research to drug abuse and addiction. It is expected that a Center will transform knowledge in the sciences it is studying. Incremental work should not be the focus of Center activities; rather, new and creative directions are encouraged. An application should integrate and promote research in existing funded projects, to achieve new and creative directions. It is expected that individual core activities reflect a relationship to the integrating theme of the Center and the Center is expected to provide research opportunities and experiences to new investigators, and share findings, data and their resources, consistent with achieving the goals of the program.