NIH Weekly Funding Opportunities and Policy Notices
Notice NOT-TR-20-037 from the NIH Guide for Grants and Contracts
Notice NOT-RM-20-025 from the NIH Guide for Grants and Contracts
Funding Opportunity PAR-20-301 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to support intramural-extramural collaborations on late-stage translational science projects between NCATS Therapeutic Development Branch (TDB) and extramural researchers, for therapeutic development of small molecules, biologics, or gene therapies. The UG3 phase will provide support for late stage pre-clinical work and clinical trial planning that is conducted at applicant institutions. The goal of any collaboration with TDB is to enable an IND application by the end of the UG3 phase. If UG3 milestones are met and an IND is cleared, support may be provided for an early stage clinical trials in the UH3 phase that will be conducted at the applicant institutions.
Funding Opportunity RFA-CA-20-043 from the NIH Guide for Grants and Contracts. Through this funding opportunity announcement (FOA), the National Cancer Institute (NCI) invites multiple-PD/PI applications for collaborative research projects that will comprise a new incubator program within the Cancer Intervention and Surveillance Modeling Network (CISNET). The overarching goal of this FOA is to expand comparative simulation modeling approaches developed by CISNET to cancer sites beyond the sites which have been previously funded under CISNET (breast, colorectal, prostate, lung, esophageal, and cervical). This "incubator" FOA is open to any cancer site beyond these sites. Specifically, this program aims to translate CISNETs framework of success to cancer sites that are not already part of the CISNET and for which there has been nascent/limited population modeling and little to no comparative modeling. For this FOA, "incubate" refers to accelerating the development and application of CISNET-type models for new cancer sites. Accelerating the development of comparative simulation modeling approaches for new cancer sites beyond those already funded is expected to generate sophisticated, evidence-based decision tools that could inform decisions on the most efficient utilization of existing and emerging technologies and strategies for the control of proposed cancers. While open to all qualified investigators, to encourage broad participation from population modelers in cancer control, this FOA will allow no more than one Principal Investigator who is funded under the CISNET FOA RFA-CA-19-054 to also be a Principal Investigator on each Incubator application.
Funding Opportunity PAR-20-289 from the NIH Guide for Grants and Contracts. The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The overarching goal of this NIAID R25 program is to support educational activities that complement and/or enhance the training of a workforce to meet the nations biomedical, behavioral and clinical research needs of NIAID mission areas.
Funding Opportunity RFA-MH-20-556 from the NIH Guide for Grants and Contracts. This FOA is related to the transformative project, "A Cell Type-Specific Armamentarium for Understanding Brain Function and Dysfunction," described in the "The BRAIN Initiative 2.0: From Cells to Circuits, Toward Cures" report of the Advisory Committee to the NIH Director BRAIN Initiative Working Group 2.0.
Funding Opportunity RFA-NS-21-010 from the NIH Guide for Grants and Contracts. Reissue of RFA-NS-20-010: The purpose of this funding opportunity announcement (FOA) is to support preclinical optimization and development of safe, effective, and non-addictive small molecule and biologic therapeutics to treat pain. The goal of the program is to accelerate the optimization and development of promising small molecule and biologic hits/leads towards clinical trials. Applicants must have a promising hit/lead, robust biological rationale for the intended approach, and identified assays for optimization of the agent. The scope of this program includes optimization and early development activities, IND-enabling studies, and assembly of Investigational New Drug (IND) application. This is a milestone-driven phased cooperative agreement program involving participation of NIH program staff in the development of the project plan and monitoring of research progress.
Notice NOT-OD-20-174 from the NIH Guide for Grants and Contracts
Notice NOT-HL-20-814 from the NIH Guide for Grants and Contracts
Funding Opportunity RFA-TR-20-031 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to support basket clinical trials of drugs targeting shared molecular etiologies in more than one rare disease.
Funding Opportunity RFA-TR-20-032 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to support basket clinical trials of drugs targeting shared molecular etiologies in more than one rare disease. To facilitate clinical trial start up, and leverage existing datasets, preference will be given to applications focusing on diseases that are under study by the Rare Disease Clinical Research Network (RDCRN), and that involve collaborations with RDCRN clinical investigators.
Funding Opportunity RFA-CA-20-051 from the NIH Guide for Grants and Contracts. The purpose of this RFA is to solicit applications to develop, adapt, and test individual-, community- or multilevel interventions to address modifiable risk factors for cancer in rural populations. Proposals should focus on primary prevention and assess and address one or more of the social and behavioral risk factors that contribute to cancer disparities in rural populations. Proposals should also assess and address myriad social determinants of health, cultural factors, and health care and technology access barriers that may contribute to rural cancer disparities. To date, there have been few intervention studies to address social and behavioral risk factors for cancer specifically in rural populations, and very little has been published on addressing the modifiable, non-geographic aspects of rurality that may contribute variance to cancer-related outcomes in rural populations. This FOA also encourages implementation science research, to incorporate efficacious cancer control interventions in a coordinated way, into broader, sustainable health programs that are designed to reach rural populations and allow local customization and adaption. The greater availability of granular data and better understanding of issues related to place (geospatial factors) will allow for local customization and adaptation of interventions, where appropriate. It is equally important that interventions be designed to strengthen or enhance existing, sustainable programs that can be expanded to have a downstream effect on population health. Applicants are strongly encouraged to collaborate with organizations and programs with experience or infrastructure (e.g., telemedicine, behavioral health services) designed to address other health or social problems in rural populations that could afford substantial opportunities to cancer prevention and control investigators. Examples include, but are not limited to, Federally Qualified Health Centers, community health centers, rural health centers
Notice NOT-OH-20-010 from the NIH Guide for Grants and Contracts
Notice NOT-OH-20-012 from the NIH Guide for Grants and Contracts
Notice NOT-OH-20-009 from the NIH Guide for Grants and Contracts
Notice NOT-NS-20-108 from the NIH Guide for Grants and Contracts
Notice NOT-CA-20-099 from the NIH Guide for Grants and Contracts
Notice NOT-OH-20-011 from the NIH Guide for Grants and Contracts
Funding Opportunity PAR-20-304 from the NIH Guide for Grants and Contracts. NLM wishes to accelerate the availability of and access to secure, complete data sets and computational models that can serve as the basis of transformative biomedical discoveries by improving the speed and scope of the curation processes.
Notice NOT-HS-20-016 from the NIH Guide for Grants and Contracts