NIH Weekly Funding Opportunities and Policy Notices
Notice NOT-GM-23-013 from the NIH Guide for Grants and Contracts
Notice NOT-AI-23-002 from the NIH Guide for Grants and Contracts
Notice NOT-OD-23-016 from the NIH Guide for Grants and Contracts
Notice NOT-CA-23-011 from the NIH Guide for Grants and Contracts
Notice NOT-GM-23-014 from the NIH Guide for Grants and Contracts
Notice NOT-CA-23-010 from the NIH Guide for Grants and Contracts
Notice NOT-GM-23-009 from the NIH Guide for Grants and Contracts
Funding Opportunity PAR-23-041 from the NIH Guide for Grants and Contracts. The purpose of this initiative is to support projects which exploit genome or epigenome editing to functionally validate and characterize genes or variants involved in substance use disorder-relevant phenotypes. It is expected that any genetic resources generated will be made broadly available to the scientific community to enable investigation of the relevant neurobiological mechanisms involved and provide critical foundational knowledge for the development of future prevention, diagnostic, and therapeutic strategies.
Notice NOT-AT-23-004 from the NIH Guide for Grants and Contracts
Notice NOT-HL-22-055 from the NIH Guide for Grants and Contracts
Notice NOT-EB-22-011 from the NIH Guide for Grants and Contracts
Funding Opportunity PAR-23-033 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to support translation of advanced HIV-1 vaccine candidates from pre-clinical studies through different phases of process and product development, Current Good Manufacturing Practice (CGMP) manufacturing and regulatory filing to the point of clinical testing. The FOA will support technology transfer, preclinical immunogenicity and optimization studies, process development, analytical assay development, qualification, validation, testing, small scale pilot or engineering runs, CGMP manufacture in partnership with Pharma/Biotech/Contract Manufacturing Organizations (CMO), quality assurance/quality control oversight, fill-finish activities, product release and storage, generation of reference standard, drug substance and drug product stability testing programs, Investigational New Drug (IND)-enabling studies, regulatory submission preparation.
Funding Opportunity PA-23-044 from the NIH Guide for Grants and Contracts. The National Institutes of Health (NIH) hereby notify Principal Investigators holding specific types of NIH research grants, listed in the full Funding Opportunity Announcement (FOA) that funds may be available for competitive revisions to meet immediate needs to help address a specific public health crisis in a timely manner, but that were unforeseen when the new or renewal application or grant progress report for non-competing continuation support was submitted. Applications for Urgent Competitive Revisions will be routed directly to the NIH awarding component listed on the NoA of the most recent parent award.
Funding Opportunity RFA-CA-23-019 from the NIH Guide for Grants and Contracts. The objectives of the Early Detection Research Network (EDRN; edrn.cancer.gov) are to discover, develop and validate biomarkers and imaging methods to detect early stage cancers and to translate these into clinical tests. The EDRN provides an infrastructure that is essential for this process and has successfully completed more than 10 multicenter validation studies.
Funding Opportunity RFA-CA-23-018 from the NIH Guide for Grants and Contracts. The purpose of this initiative is to establish an Academic-Industrial Partnership Program to develop new and/or validate existing technologies, methods, and assays for the capture and quantification of tumor associated cells, DNA, RNA, or exosomes in body fluids of patients with early stage disease or those at high risk; as well as distinguishing cancer from benign disease; or aggressive from indolent cancers. The precompetitive alliances with industry will harmonize and validate technologies, methods and assays associated with liquid biopsies.
Notice NOT-CA-22-142 from the NIH Guide for Grants and Contracts
Notice NOT-GM-23-011 from the NIH Guide for Grants and Contracts
Funding Opportunity PAR-22-252 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is to support preclinical HIV/AIDS research using NHP models performed by Early Stage Investigators (ESIs) who are within 10 years of their terminal degree or completion of their residency training but who have at least two years of postdoctoral experience. The goal of this support is to help advance HIV/AIDS researchers using NHP models in preclinical research by providing a degree of independence for these ESIs to develop new research directions and to position these researchers to be competitive for new research funding (e.g., R01). Proposed projects must use NHPs as preclinical models for HIV/AIDS research This funding initiative encompasses all priorities of the fiscal year (FY) 2021-2025 NIH Strategic Plan for HIV and HIV-Related Research (https://www.oar.nih.gov/hiv-policy-and-research/strategic-plan): reduce the incidence of HIV; develop next-generation HIV therapies; conduct research toward HIV cure; address HIV-associated comorbidities, coinfections, and complications; and advance cross-cutting areas of research.
Funding Opportunity PAR-23-040 from the NIH Guide for Grants and Contracts. The Office of Research Infrastructure Programs (ORIP) encourages research project grant applications aimed at developing and implementing broadly applicable technologies, tools, and resources for validating animal models and enhancing rigor, reproducibility, and translatability of animal research. Research projects submitted under this Funding Opportunity Announcement (FOA) should be hypothesis driven with strong preliminary data. Proposed studies, models, resources, or technologies under this FOA must either address research interests of multiple NIH Institutes and Centers (ICs), explore multiple organ systems, or be applicable to diseases and processes that impact multiple organ systems in order to align with ORIPs NIH-wide mission and programs. Applications should aim to enhance the rigor, reproducibility, and translatability of animal research through the development and implementation of technologies, tools, and resources that have significant impact across a broad range of research areas using animal models. Applications must demonstrate how the proposed resources and technologies impact rigor and reproducibility of animal studies.
Funding Opportunity PAR-23-039 from the NIH Guide for Grants and Contracts. The Office of Research Infrastructure Programs (ORIP) encourages resource-related research grant applications aimed at developing broadly applicable technologies, tools, and resources for validating animal models and enhancing rigor, reproducibility, and translatability of animal research. Proposed studies, models, resources, or technologies submitted under this Funding Opportunity Announcement (FOA) must either address research interests of multiple NIH Institutes and Centers (ICs), explore multiple organ systems, or be applicable to diseases and processes that impact multiple organ systems in order to align with ORIPs NIH-wide mission and programs. Applications should aim to enhance the rigor, reproducibility, and translatability of animal research through the development of technologies, tools, and resources that have significant impact across a broad range of research areas using animal models. Applications must demonstrate how the proposed resources and technologies impact rigor and reproducibility of animal studies. Applications for developing a limited quantity of resources are not suitable for this FOA.