NIH Weekly Funding Opportunities and Policy Notices
Funding Opportunity RFA-AR-24-001 from the NIH Guide for Grants and Contracts. NIAMS Skin Biology and Diseases Resource-based Centers (P30 - Clinical Trial Not Allowed)
Notice NOT-NS-23-056 from the NIH Guide for Grants and Contracts
Notice NOT-CA-23-029 from the NIH Guide for Grants and Contracts
Funding Opportunity RFA-TR-23-001 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is to establish Centers to support research that will accelerate the translational use of Microphysiological Systems (MPS) in drug development through regulatory acceptance and adoption for industrial use, by establishing MPS that are fit-for-purpose for industry needs and have specific defined contexts of use (CoUs) and will be developed with consideration of applicable expectations to achieve regulatory approval. For this FOA, the term drugs refers to both human pharmacological and biological products unless otherwise specified. These Centers will further the development of MPS as drug development tools (DDTs) that, once qualified, will be made publicly and commercially available to fill unmet needs in drug development.
Notice NOT-NS-23-043 from the NIH Guide for Grants and Contracts
Notice NOT-CA-23-028 from the NIH Guide for Grants and Contracts
Funding Opportunity RFA-PM-23-002 from the NIH Guide for Grants and Contracts. The All of Us Research Program (All of Us) within the Office of the Director (OD) encourages investigators to apply for grant applications that will advance research in high-priority mission areas of the Institutes, Centers, and Offices (ICOs) through two companion FOAs (1) one to use standard methods and approaches to analyze currently available data within the All of Us Research Programs Researcher Workbench and (2) one to develop new methods, models, and tools and use them to analyze data in the Researcher Workbench. The new tools will be made broadly available to the scientific community. This FOA uses the R03 grant mechanism to support data analysis using standard methods, while the companion FOA (link) uses the R21 mechanism for new tool development and application.
Funding Opportunity RFA-AG-24-024 from the NIH Guide for Grants and Contracts. This RFA supports a national survey of professional dementia care providers and link consented survey respondents (providers and institutional representative) that consent to administrative data (e.g., electronic health records, claims, payroll, other institutional and state level data). This new resource anticipates the integration from administrative sources with the provider survey to expand research on the dementia care workforce, supply of skilled labor, and provide deeper insight into how professional care providers and institutions provide care for persons living with dementia. The national survey will oversample individuals from populations underrepresented in research on Alzheimers disease and related dementias (AD/ADRD) who serve in various professional caregiving roles (e.g., physicians, other care providers such as licensed practical nurses [LPNs], social workers) and institutions serving predominately underrepresented populations. This will allow examination of how the characteristics of professional care providers and the institutions employing them lead to variation in care provided to persons living with dementia and identify modifiable organization and individual behaviors that can improve overall health care delivery and eliminate AD/ADRD disparities.
Funding Opportunity RFA-DK-22-023 from the NIH Guide for Grants and Contracts. The NIDDK Inflammatory Bowel Disease Genetics Consortium (IBDGC), in collaboration with the International IBD Genetics Consortium, has identified over 250 susceptibility loci for IBD. The IBDGC has recently been renewed with a continued mission to characterize the genetic architecture of IBD phenotypes in diverse populations and to elucidate the biological mechanisms by which genetic variants influence IBD pathophysiology and clinical course. However, current resources permit functional investigation of only a limited number of loci, genes and physiological domains, while the biological mechanisms underlying most of the identified IBD risk loci remain unknown. The purpose of this Funding Opportunity Announcement (FOA) is to expand the number of IBD susceptibility loci, causal variants and effector genes, and IBD-related phenotypes and physiological domains under investigation via Ancillary Studies utilizing the extensive resources including subjects, samples and datasets established by the IBDGC. Proposed Ancillary Studies should focus on causal variant identification and/or functional characterization of effector genes within IBD risk loci and must not duplicate studies either ongoing or already completed by the IBDGC.
Funding Opportunity PAR-23-075 from the NIH Guide for Grants and Contracts. The NIH Common Fund has established the Gabriella Miller Kids First Pediatric Research Program (Kids First) to develop a pediatric research data resource populated by genome sequence and phenotypic data that will be of high value for the communities of investigators who study the genetics of childhood cancers and/or structural birth defects. Kids First has established and continues to develop a Data Resource including a collection of curated genomic and phenotypic data from childhood cancer and structural birth defects cohorts and a central portal where these data and analysis tools are accessible to the research community. Access to these data will promote comprehensive and cross-cutting research and collaboration leading to more refined diagnostic capabilities and ultimately more targeted therapies. This FOA is intended to support meritorious small research projects focused on analyses of childhood cancer and/or structural birth defects genomic datasets generated by the Kids First program and/or associated phenotypic datasets. Development of approaches, tools, or algorithms appropriate for analyzing genomic, phenotypic, and/or clinical data relevant to Kids First may also be proposed.
Funding Opportunity PAR-23-083 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to 1) invite research grant applications that enable the collection of pilot data to support early stage testing of promising pharmacological and non-pharmacological interventions for cognitive and neuropsychiatric changes associated with age-related cognitive decline and Alzheimer's disease (AD) and Alzheimer's disease-related dementias (ADRD) across the spectrum from pre-symptomatic to more severe stages of disease, and 2) stimulate studies to enhance trial design and methods.
Funding Opportunity PAR-23-081 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to 1) invite applications that propose to develop and implement early to late stage clinical trials of promising pharmacological and non-pharmacological interventions for cognitive and neuropsychiatric changes associated with age-related cognitive decline and Alzheimer's disease (AD) and Alzheimer's disease-related Dementias (ADRD) across the spectrum from pre-symptomatic to more severe stages of disease, and 2) stimulate studies to enhance trial design and methods.
Funding Opportunity RFA-PM-23-001 from the NIH Guide for Grants and Contracts. The All of Us Research Program (All of Us) within the Office of the Director (OD) encourages investigators to apply for grant applications that will advance research in high-priority mission areas of the Institutes, Centers, and Offices (ICOs) through two companion FOAs (1) one to use standard methods and approaches to analyze currently available data within the All of Us Research Programs Researcher Workbench and (2) one to develop new methods, models, and tools and use them to analyze data in the Researcher Workbench. The new tools will be made broadly available to the scientific community. This FOA uses the R21 grant mechanism for new tool development and application, while the companion FOA (link) uses the R03 grant mechanism to support data analysis using standard methods.
Notice NOT-MH-23-115 from the NIH Guide for Grants and Contracts
Notice NOT-OD-23-050 from the NIH Guide for Grants and Contracts
Notice NOT-GM-23-030 from the NIH Guide for Grants and Contracts
Notice NOT-GM-23-029 from the NIH Guide for Grants and Contracts
Notice NOT-DA-22-086 from the NIH Guide for Grants and Contracts
Notice NOT-OD-23-049 from the NIH Guide for Grants and Contracts
Notice NOT-OD-23-045 from the NIH Guide for Grants and Contracts