NIH Weekly Funding Opportunities and Policy Notices
Notice NOT-DA-23-015 from the NIH Guide for Grants and Contracts
Notice NOT-CA-23-015 from the NIH Guide for Grants and Contracts
Funding Opportunity PAR-23-084 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites applications for implementation of investigator-initiated clinical trials requiring an extended project period of 6 or 7 years. The trials can be any phase, must be hypothesis-driven, and related to the research mission of the participating IC. Consultation with IC staff is strongly encouraged prior to the submission of the clinical trial implementation application. This FOA is not intended for support of clinical trials that do not require an extended project period of 6 or 7 years.
Funding Opportunity RFA-MH-23-170 from the NIH Guide for Grants and Contracts. The proposed FOA would solicit applications focused on enhancing the potency of established adolescent mental health treatments through the use of developmentally informed and theoretically grounded JITAIs. While JITAIs could be applied to established interventions across the lifespan, we propose focusing specifically on adolescence - a developmental period characterized by heightened risk for new onset or worsening mental illness, poor engagement with face-to-face interventions, and peak engagement with technology. JITAIs have the potential to capitalize on adolescents near ubiquitous use of technology to facilitate symptom reduction and behavior change by providing content via an intrinsically motivating platform, facilitating skills practice in ecologically-valid contexts, tailoring the intervention to match the adolescents needs and preferences, providing in-the-moment feedback and reinforcement, and scaffolding adolescents in real time to mitigate impairments. Recent technological advancements have greatly improved the feasibility of delivering JITAIs, and these interventions have shown promise in a variety of health and addiction domains. Yet, no studies of JITAIs for adolescent mental disorders have been published to date, highlighting the need for research in this emerging area of intervention science.
Funding Opportunity PAR-23-076 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) is to provide support for research Centers that (1) conduct drug abuse and addiction research in any area of NIDAs mission, (2) have outstanding innovative science, (3) are multidisciplinary, thematically integrated, synergistic, and (4) serve as national resource(s) to provide educational and outreach activities to drug abuse research communities, educational organizations, the general public, and policy makers in the NIDA research fields. It is expected that a Center will transform knowledge in the sciences it is studying. Incremental work should not be the focus of Center activities; rather, new and creative directions are required. The P50 Center of Excellence is expected to foster the career development and mentoring of new investigators who would be given meaningful roles to play in the Center projects. A goal of this program is to create NIDA Centers that are national community resources for furthering drug abuse research by sharing their findings, their data, and their resources as appropriate for researchers to use and build upon and to advance research in this field.
Notice NOT-NS-23-057 from the NIH Guide for Grants and Contracts
Notice NOT-OD-23-056 from the NIH Guide for Grants and Contracts
Notice NOT-DK-23-008 from the NIH Guide for Grants and Contracts
Funding Opportunity PAR-23-074 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to encourage applications to phenotype and/or perform research on embryonic lethal knockout (KO) mouse strains being generated through the International Mouse Phenotyping Consortium (IMPC) of which the NIH Knockout Mouse Phenotyping Program (KOMP2) is a member. The mission of IMPC is to generate a comprehensive catalogue of mammalian gene function that will provide the foundation for functional analyses of human genetic variation. The current (July 19, 2022) IMPC data release includes phenotypic data for 8260 knockout genes. Overall, the IMPC hopes to generate a null mutant and undertake broad-based phenotyping for every gene in the mouse genome. About 30% of these strains are expected to be either embryonic or perinatal lethal, or subviable. However, a large portion of homozygous lethal mutations are expected to have viable heterozygous phenotypes. The scientific community has the unique opportunity to leverage these mouse strains while they are being created and bred as part of the IMPC adult mouse phenotyping effort to perform additional in-depth phenotyping and research.
Notice NOT-NS-23-046 from the NIH Guide for Grants and Contracts
Notice NOT-HS-23-006 from the NIH Guide for Grants and Contracts
Funding Opportunity RFA-AG-24-001 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites applications from institutions proposing to develop, or renew, an Alzheimer's Disease Research Center (ADRC). The National Institute on Aging (NIA) funds ADRCs at major medical institutions across the United States. NIA-funded ADRCs serve as a national resource for research related to Alzheimers disease (AD) and AD-related dementias (ADRD). Additionally, ADRCs work to translate research advances into improved diagnosis and care, as well as find ways to treat, and possibly prevent, AD/ADRD. Lastly, ADRCs collaborate and coordinate their research efforts with other programs and investigators funded by the National Institutes of Health (NIH).
Funding Opportunity RFA-ES-23-002 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to support resource projects to enable Environmental Health Sciences (EHS) communities to openly develop, extend, adapt, or refine data and metadata standards as well as associated tools to implement standards. The initiative is intended to catalyze community-driven standards development and related implementation in environmental health. Projects can support activities at any point in the data standards lifecycle and should build on existing resources, infrastructure, and partnerships whenever possible. The standards, software, best practices, or other tools developed should be broadly disseminated for adoption by the relevant biomedical communities.
Notice NOT-EB-22-016 from the NIH Guide for Grants and Contracts
Notice NOT-DA-23-014 from the NIH Guide for Grants and Contracts
Notice NOT-CA-23-036 from the NIH Guide for Grants and Contracts
Notice NOT-CA-23-030 from the NIH Guide for Grants and Contracts
Funding Opportunity PAR-23-082 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites applications that employ integrative experimental and analytical approaches engaging basic and translational/clinical research aimed at developing a comprehensive understanding of the impact of sex differences on the trajectories of brain aging and disease, phenotypes of AD and AD-related dementias (ADRD) risk, individualized prevention, and responsiveness to pharmacologic and non-pharmacologic interventions. To this end, the central goal of this initiative is to develop robust research programs that will explore how genes, environment, and host factors such as hormonal status (gonadal and brain-derived) interact at various levels of biologic complexity (i.e., cell, tissue, organs/organ systems, and populations) to produce heterogeneous phenotypes of disease risk and responsiveness to prevention/therapy in AD/ADRD.
Funding Opportunity PAR-23-064 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) announces the availability of support for collaborative research by multi-disciplinary teams which is of high priority to NIDA and leads to synergistic outcomes based on the synthesis of multiple research approaches. The NIDA Program Projects funding opportunity will support research in which the funding of three or more highly meritorious projects as a group enriches both the component projects and the overall program to offer significant scientific advantages over supporting the same projects as individual research grants (i.e., synergy). For the duration of the award, each Program must consist of a minimum of three research projects focused on issues critical to advance the mission and goals of NIDA.
Notice NOT-TW-23-001 from the NIH Guide for Grants and Contracts