NIH Weekly Funding Opportunities and Policy Notices
Funding Opportunity PAR-17-293 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) is designed to facilitate clinical trials that can be completed within a limited timeframe and budget. A broad range of types of exploratory studies may be submitted to this FOA. The trials must address research questions related to the mission and goals of the NIAMS and may evaluate interventions with drugs, biologics, devices, or surgical, dietary, behavioral or rehabilitation therapies.
Funding Opportunity RFA-AI-17-013 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages exploratory and developmental bi-phasic research applications to support the identification and optimization of small molecules or RNAs that interact with host epigenetic machinery to mediate long-term or permanent epigenetic silencing of HIV-1 proviruses
Funding Opportunity RFA-HL-18-010 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to encourage innovative molecular and physiological research that could lead to early diagnosis or effective medical therapy for calcific aortic valve disease (CAVD). Applications from investigators in related fields (for example, mineralization and bone physiology, extracellular matrix physiology, and molecular imaging) are strongly encouraged.
Funding Opportunity RFA-AT-18-001 from the NIH Guide for Grants and Contracts. The purpose of this FOA is to solicit applications to examine the impact of behavioral interventions within the context of states plans for use of the SAMHSA Opioid STR grant funds authorized under the 21st Century Cures Act. Applications are encouraged for studies that examine the impact of interventions such as mindfulness meditation, cognitive behavioral therapy, or multi-disciplinary rehabilitation for primary or secondary prevention for opioid use disorder (OUD) or as an adjunct to medication assisted treatment (MAT) of OUD. Applications that emphasize treatment of the comorbidity of OUD and chronic pain are of particular interest.
Funding Opportunity RFA-HL-18-009 from the NIH Guide for Grants and Contracts. The purpose of this FOA is to provide access to a consultative resource for planning activities for late phase (phase II and beyond) single-site or multi-site investigator-initiated clinical trials that address critical clinical questions within the mission of the National Heart, Lung, and Blood Institute (NHLBI) and that require non-traditional clinical trial designs with the opportunity for statistical novelty and/or innovation. The FOA will support the development of feasible and well-designed clinical trials utilizing consultative services provided by the Innovative Clinical Trials Resource (ICTR) (N01).
Funding Opportunity RFA-HL-18-008 from the NIH Guide for Grants and Contracts. The purpose of this FOA is to provide support for planning activities for late phase (phase II and beyond) single-site or multi-site investigator-initiated clinical trials that address critical clinical questions within the mission of the National Heart, Lung, and Blood Institute (NHLBI) and that require non-traditional clinical trial designs with the opportunity for statistical novelty and/or innovation. The FOA will support the development of feasible and well-designed clinical trials utilizing consultative services provided by the Innovative Clinical Trials Resource (ICTR) (N01).
Funding Opportunity PA-17-291 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement is to support studies that will evaluate HIV drug resistance and its relationship to treatment success. Applications are sought proposing studies of genotype/phenotype correlations in diverse subtypes, the relationship between minority variants and treatment outcomes and on the reasons for the discordance between genotype and treatment success or failure. Laboratory evaluations of samples with clinical correlates in patients on recommended regimens are encouraged.
Funding Opportunity PA-17-292 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity is to support studies that will evaluate HIV drug resistance and its relationship to treatment success. Applications are sought proposing studies of genotype/phenotype correlations in diverse subtypes, the relationship between minority variants and treatment outcomes and on the reasons for the discordance between genotype and treatment success or failure. Laboratory evaluations of samples with clinical correlates in patients on recommended regimens are encouraged.
Funding Opportunity RFA-DK-17-006 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites applications for a Center for Identification and Study of Individuals with Atypical Diabetes Mellitus (U54). The purpose of this Center is to: foster the study of individuals with rare/atypical forms of diabetes mellitus; identify and analyze phenotypic and genotypic defects that may provide insights into more common, heterogeneous forms of Type 2 diabetes mellitus (T2DM) in the general population; and develop a community resource to advance research in this area through the collection and dissemination of data and samples for access by the broad research community. To achieve this goal, the Center should support the following primary research endeavors: (1) develop a process for identifying and studying individuals/families with rare and uncharacterized forms of diabetes and (2) create and manage a database and biospecimen repository of rare/atypical forms of diabetes for use by the broader research community in future analyses.
Funding Opportunity PAR-17-290 from the NIH Guide for Grants and Contracts. The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching goal of this NIA R25 program is to support educational activities that enhance the diversity of the biomedical, behavioral and clinical research workforce in aging.
Funding Opportunity PA-17-289 from the NIH Guide for Grants and Contracts. The goal of this Funding Opportunity Announcement (FOA) is to efficiently use the existing cancer registry infrastructure by augmenting data already collected with additional information needed to understand health disparities among people diagnosed with cancer. Specifically, this FOA will support the study of factors influencing observed health disparities within the framework of population-based cancer registries by the inclusion of data not routinely collected by or linked to the registries. The studies should be hypothesis-driven and multidisciplinary approaches are encouraged. Investigators are encouraged to leverage the data already collected by the registries to investigate the determinates of health disparities. The goal of these analyses will be to understand why disparities in cancer treatment and outcomes persist by identifying factors contributing to disparities and their relative importance.
Funding Opportunity PA-17-288 from the NIH Guide for Grants and Contracts. The goal of this Funding Opportunity Announcement (FOA) is to efficiently use the existing cancer registry infrastructure by augmenting data already collected with additional information needed to understand health disparities among people diagnosed with cancer. Specifically, this FOA will support the study of factors influencing observed health disparities within the framework of population-based cancer registries by the inclusion of data not routinely collected by or linked to the registries. The studies should be hypothesis-driven and multidisciplinary approaches are encouraged. Investigators are encouraged to leverage the data already collected by the registries to investigate the determinates of health disparities. The goal of these analyses will be to understand why disparities in cancer treatment and outcomes persist by identifying factors contributing to disparities and their relative importance.
Funding Opportunity RFA-AA-18-001 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites applications for specialized Alcohol Research Centers using the P50 mechanism. The overall purpose of the NIAAA Alcohol Research Center program is to provide leadership in conducting and fostering interdisciplinary, collaborative research on a wide variety of topics relevant to the Institutes mission. These topics include, but are not limited to: the nature, etiology, genetics, diagnosis, treatment, and prevention of alcohol use disorders and their biomedical, psychosocial, and economic consequences across the lifespan. Centers also are regional or national resources that contribute to the development of new research methods, technologies and approaches that sustain innovative goal-directed research.
Notice NOT-RM-17-022 from the NIH Guide for Grants and Contracts
Funding Opportunity RFA-DK-17-009 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to support an ancillary study grant application(s) to add psychological, behavioral, and/or neurocognitive assessments to the data collection in adults ( 18 years of age) enrolled at the clinical sites in the Molecular Transducers of Physical Activity in Humans Consortium (MoTrPAC) supported by the NIH Common Fund. This ancillary study FOA complements the parent MoTrPAC study by supporting research to elucidate the individual level psychological, behavioral, and neurocognitive characteristics that explain variation in individual response and adherence to a program of physical activity. The ultimate goal of the research supported by this FOA is to characterize individual differences in response to exercise over the course of the MoTrPAC protocol in order to identify novel treatment targets and inform personalized physical activity intervention approaches in the future.
Funding Opportunity RFA-ES-17-004 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages Small Business Innovation Research (SBIR) grant applications from small business concerns (SBCs) that propose to further the development of Advanced Technology Training (ATT) products for the health and safety training of hazardous materials (HAZMAT) workers; skilled support personnel; emergency responders in biosafety response, infectious disease training and cleanup; emergency responders in disasters and resiliency training; and for ATT tools to assist in research into the acute and long-term health effects of environmental disasters. ATT as defined by the Worker Training Program (WTP) includes, but is not limited to, online training, virtual reality, and serious gaming, which complement all aspects of training from development to evaluation including advance technologies that enhance, supplement, improve, and provide health and safety training for hazardous materials workers. These products must complement the goals and objectives of the WTP http://www.niehs.nih.gov/careers/hazmat/about_wetp/. The major objective of the NIEHS WTP is to prevent work related harm by assisting in the training of workers in how best to protect themselves and their communities from exposure to hazardous materials. The financial support for this initiative comes directly from NIEHS Worker Education and Training Branch SBIR funds.
Funding Opportunity RFA-MH-18-400 from the NIH Guide for Grants and Contracts. This funding opportunity announcement (FOA) seeks to leverage data from existing basic, clinical, and intervention research on suicide risk and behaviors as well as social media and healthcare records data, by encouraging the integration of existing data sets for novel secondary analyses aimed at identifying potential biological, experiential, and other predictors and moderators of suicide risk. The use of dimensional variables and inclusion of multiple levels of analyses is particularly encouraged. A secondary goal of this FOA is to support innovative projects that will generate foundational work for research studies on suicide-related behaviors that inform a Research Domain Criteria (RDoC) approach in this area. Projects supported by this FOA will help address gaps identified in the 2014 Prioritized Research Agenda for Suicide Prevention.
Notice NOT-DE-17-009 from the NIH Guide for Grants and Contracts
Notice NOT-DA-17-039 from the NIH Guide for Grants and Contracts
Funding Opportunity PAR-17-287 from the NIH Guide for Grants and Contracts. The objective of the NIA Academic Leadership Career Award (K07) is to provide support for senior investigators who have the expertise and leadership skills to enhance aging and geriatric research capacity within their academic institution.