NIH Weekly Funding Opportunities and Policy Notices
Notice NOT-PM-19-001 from the NIH Guide for Grants and Contracts
Notice NOT-OD-19-039 from the NIH Guide for Grants and Contracts
Funding Opportunity RFA-AI-18-058 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to apply genetic engineering technologies to HIV-1 cure research. Gene- and/or cell-based approaches are sought that can achieve long term remission of HIV-1 in the absence of antiretroviral treatment or complete elimination of HIV-1. Applications are expected to include basic science/preclinical research as well as translational activities such as test-of-concept studies in animal models or human subjects and must be designed as collaborative efforts between academia and the private sector.
Funding Opportunity RFA-MH-19-225 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement is to support a practice-based research network in the United States to transform the development, delivery, and sustainability of evidence-based mental health practices and services. Through a research consortium embedded within large and integrated healthcare delivery systems (public and/or commercial systems) that serve representative populations, this Network would result in a continuously learning healthcare system as defined by the Institute of Medicine, to create a continuous cycle or feedback loop in which scientific evidence informs clinical practice while data gathered from clinical practice and administrative sources inform scientific investigation.
Notice NOT-AG-18-051 from the NIH Guide for Grants and Contracts
Funding Opportunity PA-19-096 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to encourage research to advance the understanding of natural history of infection for three sexually transmitted infections (STIs): gonorrhea, syphilis, and chlamydia. This research opportunity encourages studies that address the natural history of infection in the context of either: 1) correlates of protection, 2) host response to infection, 3) clinical endpoints of disease, or 4) biological and clinical factors that influence clearance rather than persistence of infection.
Funding Opportunity PA-19-094 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages applications for mechanistic research on age-related changes in emotion regulation and how they may contribute to mental disorders in middle-aged and older adults.In particular, research is sought that will advance understanding of irregularities in the integrative neural-behavioral mechanisms of emotion regulation in adult mood and anxiety disorders, and that will examine whether the irregularities are associated with typical or atypical maturational trajectories of emotion processing. If older adults who suffer episodes of affective dysregulation share the same patterns of improved emotional function with age as have been found to be typical of the older adult population in general. Research that helps to clarify whether they do or do not manifest typical emotion processing trajectories may lead to very different understanding of the irregularities involved their dysregulation.It is anticipated that such studies may identify novel targets for mental health interventions or prevention efforts, or provide clues as to which available intervention strategies might be optimally applied to normalize emotion dysregulation or to strengthen emotional resilience at particular stages of the adult life cycle.
Funding Opportunity PA-19-095 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages applications for mechanistic research on age-related changes in emotion regulation and how they may contribute to mental disorders in middle-aged and older adults.In particular, research is sought that will advance understanding of irregularities in the integrative neural-behavioral mechanisms of emotion regulation in adult mood and anxiety disorders, and that will examine whether the irregularities are associated with typical or atypical maturational trajectories of emotion processing. If older adults who suffer episodes of affective dysregulation share the same patterns of improved emotional function with age as have been found to be typical of the older adult population in general, understanding of the irregularities involved their dysregulation.It is anticipated that such studies may identify novel targets for mental health interventions or prevention efforts, or provide clues as to which available intervention strategies might be optimally applied to normalize emotion dysregulation or to strengthen emotional resilience at particular stages of the adult life cycle.
Notice NOT-HL-18-666 from the NIH Guide for Grants and Contracts
Notice NOT-AG-18-050 from the NIH Guide for Grants and Contracts
Notice NOT-AG-18-048 from the NIH Guide for Grants and Contracts
Notice NOT-AG-18-049 from the NIH Guide for Grants and Contracts
Notice NOT-HL-18-667 from the NIH Guide for Grants and Contracts
Notice NOT-DE-18-030 from the NIH Guide for Grants and Contracts
Funding Opportunity PAS-19-097 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to invite applications for support of innovative basic, translational, and clinical research to identify and address the challenges to achieving hepatitis B virus (HBV) cure in the presence or absence of human immunodeficiency virus (HIV).
Funding Opportunity RFA-AG-19-029 from the NIH Guide for Grants and Contracts. This FOA encourages innovative experimental approaches to explore how dietary intervention entrains peripheral or central clocks to maintain tissue homeostasis and how circadian regulation integrates with various dietary strategies to achieve optimal health benefits.
Notice NOT-HS-19-003 from the NIH Guide for Grants and Contracts
Notice NOT-HS-19-002 from the NIH Guide for Grants and Contracts
Funding Opportunity RFA-AA-19-002 from the NIH Guide for Grants and Contracts. Through this FOA, NIAAA seeks to encourage research that can be translated into interventions in order to reduce infection and transmission of HIV. These critical goals are consistent with the FY2013 Trans-NIH Plan For HIV-Related Research (http://www.oar.nih.gov/strategicplan/fy2013/index.asp).
Funding Opportunity PA-19-086 from the NIH Guide for Grants and Contracts. The primary purpose of the NIH Mentored Clinical Scientist Research Career Development Awards (K08) program is to prepare qualified individuals for careers that have a significant impact on the health-related research needs of the Nation. This program represents the continuation of a long-standing NIH program that provides support and "protected time" to individuals with a clinical doctoral degree for an intensive, supervised research career development experience in the fields of biomedical and behavioral research, including translational research. This Funding Opportunity Announcement (FOA) is designed specifically for applicants proposing to lead basic science experimental studies involving humans, referred to in NOT-OD-18-212 as prospective basic science studies involving human participants. These studies fall within the NIH definition of a clinical trial and also meet the definition of basic research. Types of studies that should submit under this FOA include studies that prospectively assign human participants to conditions (i.e., experimentally manipulate independent variables) and that assess biomedical or behavioral outcomes in humans for the purpose of understanding the fundamental aspects of phenomena without specific application towards processes or products in mind. Studies conducted with specific applications toward processes or products in mind should submit under the companion PA-18-372.