NIH Weekly Funding Opportunities and Policy Notices
Notice NOT-DK-20-002 from the NIH Guide for Grants and Contracts
Notice NOT-HD-19-040 from the NIH Guide for Grants and Contracts
Notice NOT-DE-19-019 from the NIH Guide for Grants and Contracts
Funding Opportunity RFA-DK-19-020 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages applications from integrative teams and individual investigators for large-scale complex multi-disciplinary Functional Genomics Projects (FGPs) to determine the contributions and mechanisms underlying the contribution of associated variants for type 1 diabetes (T1D). Genome-wide association studies (GWAS) and other genomic studies of T1D have found many variants that are statistically associated with disease risk or disease protection, but they have not clearly shown which variants in genomic elements cause these effects or how they result in differences in function. Applications submitted to this RFA will systematically identify causal variants and effector transcripts associated with all known T1D risk variants, verify the role of downstream effector transcripts, build network models that explain their role(s) in T1D. These biological insights could lead to the development of reliable biomarkers and effective strategies for screening and disease prevention, rational drug design, and better tailored therapies.
Notice NOT-HL-19-724 from the NIH Guide for Grants and Contracts
Funding Opportunity PAR-20-048 from the NIH Guide for Grants and Contracts. The purpose of this initiative is to build the capacity of organizations in the US-Affiliated Pacific Islands to conduct ongoing population health research in this region.
Funding Opportunity RFA-MH-20-325 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to further validate promising EEG and eye tracking measures that showed promising performance in the recently-completed Autism Biomarkers Consortium for Clinical Trials (ABC-CT) study. The intent of the FOA is to qualify a set of measures that can be used as biomarkers to reduce heterogeneity, and/or as sensitive and reliable objective measures of social impairment in autism spectrum disorders (ASD) clinical trials. The FOA will support a multi-site consortium to conduct a study with three primary aims to replicate and extend previous characterization of the most promising EEG and eye-tracking measures, incorporating suggestions and guidance from the FDA Biomarkers Qualification Program (BQP). A key goal of the Consortium project is to provide a community resource for broad sharing of all data generated including processed/analyzed data, with rapid and timely deposition of data into the National Database for Autism Research (NDAR). All data generated in this project are expected to be deposited in NDAR and will be accessible for use by all qualified investigators. In addition, blood (DNA) samples are expected to be deposited in the NIMH Repository and Genomics Resource for future research use. The Consortium project will assess the following: (1) whether eye-tracking, EEG paradigms, or a combination of the two, have potential utility as stratification biomarkers and/or as sensitive and reliable measures of change in ASD clinical trials; (2) the relationship (correlation) of validated clinical measures (including measures of social impairment) to eye tracking or EEG paradigms; and (3) the feasibility of collecting the same biomarker measures in a younger cohort.
Notice NOT-CA-20-008 from the NIH Guide for Grants and Contracts
Notice NOT-DE-19-017 from the NIH Guide for Grants and Contracts
Notice NOT-GM-20-005 from the NIH Guide for Grants and Contracts
Notice NOT-GM-20-004 from the NIH Guide for Grants and Contracts
Notice NOT-NS-20-016 from the NIH Guide for Grants and Contracts
Notice NOT-OD-20-013 from the NIH Guide for Grants and Contracts
Notice NOT-HL-19-725 from the NIH Guide for Grants and Contracts
Notice NOT-NS-20-007 from the NIH Guide for Grants and Contracts
Notice NOT-HD-19-038 from the NIH Guide for Grants and Contracts
Notice NOT-HD-19-037 from the NIH Guide for Grants and Contracts
Notice NOT-HD-19-036 from the NIH Guide for Grants and Contracts
Notice NOT-GM-20-003 from the NIH Guide for Grants and Contracts
Notice NOT-OD-20-012 from the NIH Guide for Grants and Contracts