NIH Weekly Funding Opportunities and Policy Notices
Funding Opportunity RFA-ES-20-008 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) supports Phase I (R43), Direct to Phase II (R44), and Fast Track (R44) Small Business Innovative Research (SBIR) grant proposals from small businesses concerns (SBCs) to develop resources and approaches, including panels of cells or model organisms, that can better reflect the variability in human populations in chemical toxicity testing. Current toxicology testing is often limited to studies conducted in a small number of laboratory rodent strains, which can fail to identify clinically relevant toxicity if the conventional rodent strain is particularly resistant to the toxic effects of the test compound. Cost-effective screening systems with appropriate throughput are needed to capture the variability in responses to chemical exposure in the human population based on genetic diversity.
Funding Opportunity RFA-MH-20-401 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) supports pilot work for subsequent studies testing the effectiveness of strategies to deliver evidence-based mental health services, treatment interventions, and/or preventive interventions (EBPs) in low-resource mental health specialty and non-specialty settings within the United States. The FOA targets settings where EBPs are not currently delivered or delivered with fidelity, such that there are disparities in mental health and related functional outcomes (e.g., employment, educational attainment, stable housing, integration in the community, treatment of comorbid substance use disorders, etc.) for the population(s) served. Implementation strategies should identify and use innovative approaches to remediate barriers to provision, receipt, and/or benefit from EBPs and generate new information about factors integral to achieving equity in mental health outcomes for underserved populations.
Funding Opportunity RFA-MH-20-400 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages studies that develop and test the effectiveness of strategies for implementation and sustainable delivery of evidence-based mental health treatments and services to improve mental health outcomes for underserved populations in under-resourced settings in the United States. Studies should identify and use innovative approaches to remediate barriers to provision, receipt, and/or benefit from evidence-based practices (EBPs) and generate new information about factors integral to achieving equity in mental health outcomes for underserved populations. Research generating new information about factors causing/reducing disparities are strongly encouraged, including due consideration of the needs of individuals across the life span.
Funding Opportunity RFA-MH-21-100 from the NIH Guide for Grants and Contracts. Genome-wide association studies (GWAS) have identified statistical relationships between tens of thousands of common single nucleotide variants and over a thousand traits. Due to the correlated nature of nearby genetic variants, GWAS implicate regions of the genome and do not necessarily pinpoint the causal variant(s), gene(s) or mechanism(s) underlying the trait association. The purpose of this funding opportunity announcement is to support systematic fine-mapping of genome-wide significant risk loci associated with serious mental illnesses through robust statistical genetic and functional genomic approaches.
Notice NOT-OD-20-030 from the NIH Guide for Grants and Contracts
Notice NOT-OD-20-028 from the NIH Guide for Grants and Contracts
Funding Opportunity RFA-MH-20-555 from the NIH Guide for Grants and Contracts. The NIMH Instrumentation Program encourages applications from NIH funded investigators to purchase or upgrade a single commercially available instrument or a group of components to create an instrument that is not commercially available. Examples of instruments that might be submitted under this Funding Opportunity Announcement (FOA) include light microscopes, electron microscopes, spectrophotometers, and biomedical imagers.
Funding Opportunity RFA-MH-20-521 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites applications to enhance screening and treatment for mental and substance use disorders in HRSA Ryan White HIV/AIDS Program funded sites through implementation research, to advance the goals of the National "End the Epidemic" (EHE) initiative. This FOA is intended to support pilot or feasibility implementation studies to enhance screening and treatment of substance use or mental health disorders in the HRSA Ryan White HIV/AIDS Program. Applications seeking to conduct definitive studies should consider the companion R01 FOA at RFA-MH-20-520 .
Funding Opportunity RFA-MH-20-520 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites applications to enhance screening and treatment for mental and substance use disorders in HRSA Ryan White HIV/AIDS Program funded sites through implementation research, to advance the goals of the National "End the Epidemic" (EHE) initiative. This FOA is intended to support applications seeking to conduct definitive studies on implementation approaches to enhance screening and treatment of substance use or mental health disorders in the HRSA Ryan White HIV/AIDS Program. Applications seeking to conduct pilot or feasibility implementation studies should consider the companion R34 FOA at RFA-MH20-521
Funding Opportunity PAR-20-064 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is to invite R03 applications to support archiving and documenting existing data sets in order to enable secondary analysis of these data by the scientific community. The priority of this program is to archive data sets within the scientific mission of the NICHD; highest priority is to archive data collected with NICHD support.
Funding Opportunity RFA-MH-20-345 from the NIH Guide for Grants and Contracts. This Funding Oopportunity Aannouncement (FOA) invites pilot feasibility studies testing rapid-acting interventions to reduce severe suicide risk through clinical trials that are based in appropriate/specialized healthcare settings(e.g., emergency departments [ED], psychiatric inpatient units, other settings that meet Risk Evaluation and Mitigation Strategy approaches).
Funding Opportunity PAR-20-065 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is to promote initial establishment of basic science-clinical collaborations by providing small grants to teams of basic scientists, physician scientists, and/or clinicians. These interdisciplinary teams may include but are not limited to the following: developmental biologists, cell biologists, geneticists, genomicists, physician scientists including individuals with DVM/VMD degrees, clinicians, epidemiologists, biostatisticians, and/or bioinformaticists.
Funding Opportunity RFA-HD-21-015 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to invite applications for multidisciplinary national conferences that will inform care and facilitate research for major issues in pediatric critical care medicine. Given the nascent stage of development, the small diverse patient populations, and the rapid expansion of the field, conducting research and establishing best practices in pediatric critical care is challenging. National conferences that convene experts from across the country hold the potential to establish the frameworks necessary to overcome these obstacles. It is anticipated that such conferences will foster collaboration among different clinical disciplines, geographically and culturally diverse institutions and medical centers, professional organizations and NIH Institutes. Specifically, it is hoped that these conferences will drive the development and acceptance of uniform definitions, facilitate the determination of common data elements, identify key knowledge gaps to advance research, and/or foster discussions on how research findings can be used to best inform guidelines for patient care.
Funding Opportunity RFA-RM-20-005 from the NIH Guide for Grants and Contracts. To support projects that apply new or existing tools to monitor and/or manipulate the 4D nucleome in the context of human health and disease. Any human disease or biological process relevant to NIHs mission may be proposed including environmental exposures (e.g. addictive substances, toxins, psychosocial stress), or studies across development or lifespan. Other relevant timeframes may include but are not limited to: circadian rhythms, fasting and feeding cycles, reproductive cycles, and sleep/wake cycles.
Funding Opportunity RFA-MH-20-510 from the NIH Guide for Grants and Contracts. NIMH seeks applications for innovative research projects to test strategies to increase the reach, efficiency, effectiveness, and quality of digital mental health interventions. This FOA is intended to support the development of digital health test beds that leverage well-established digital mental health platforms ,to rapidly refine and optimize existing evidence-based digital health interventions and conduct clinical trials testing digital mental health interventions that are statistically powered to provide a definitive answer regarding the intervention's effectiveness.
Funding Opportunity RFA-RM-20-004 from the NIH Guide for Grants and Contracts. The purpose of this FOA is to solicit applications for research projects to generate reference datasets and to create navigable maps for the study of the spatial and temporal organization of the nucleus, using genomic and imaging data as well as newly developed visualization and integrative analysis tools.
Funding Opportunity RFA-RM-20-006 from the NIH Guide for Grants and Contracts. To support projects from NIH-defined New Investigators that apply new or existing tools to monitor and/or manipulate the 4D nucleome (4DN) in the context of human health and disease. Any human disease or biological process relevant to NIHs mission may be proposed including environmental exposures (e.g. addictive substances, toxins, psychosocial stress), or studies across development or lifespan. Other relevant time frames may include but are not limited to: circadian rhythms, fasting and feeding cycles, reproductive cycles, and sleep/wake cycles.
Funding Opportunity RFA-RM-20-003 from the NIH Guide for Grants and Contracts. To support the development and application of tools that would enable the monitoring in real-time of the dynamic three-dimensional structure of mammalian genomes and provide insight into how organizing components of 4D genome architecture affect biological processes in live cells.
Funding Opportunity RFA-MH-20-505 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to encourage practice-based research aimed at testing the effectiveness of developmentally-focused theory-based efficacious prevention interventions which may impact mental health outcomes, including suicide behaviors and serious mental illness. The research should test prevention approaches that are both scalable and sustainable for implementation in pediatric-serving primary care settings, with an emphasis on populations experiencing mental health disparities. This FOA seeks to supports clinical trials to establish the effectiveness of scalable prevention interventions when implemented using available resources within pediatric-serving primary care settings.
Funding Opportunity RFA-MH-20-506 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to encourage practice-based research aimed at refining and pilot testing developmentally-focused, theory-based efficacious prevention interventions that may impact mental health outcomes, including suicide behaviors and serious mental illness. The research should test prevention approaches that are both scalable and sustainable for implementation in pediatric-serving primary care settings, with an emphasis on populations experiencing mental health disparities.