NIH Weekly Funding Opportunities and Policy Notices
Notice NOT-HL-20-801 from the NIH Guide for Grants and Contracts
Notice NOT-HL-20-800 from the NIH Guide for Grants and Contracts
Notice NOT-HL-20-799 from the NIH Guide for Grants and Contracts
Funding Opportunity RFA-DK-20-019 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites applications for a Scientific Data Coordinating Center (SDCC) to support and provide scientific guidance as part of the new consortium to study Chronic Kidney Disease of UnceRtain Etiology (CKDu) in Agricultural Communities (CURE). The SDCC will guide the consortium as it develops protocols for epidemiologic studies. It will provide data management and analysis, as well as overall project management for the consortium. This collaborative research consortium will bring together a broad range of expertise and enable discovery science to understand the cause or causes of CKDu and disease progression. The consortium will also work to identify potential therapeutic targets and public health interventions. The consortium will consist of a Scientific Data Coordinating Center, Field Sites, a Renal Analytic Core and the NIEHS Human Health Exposure Analysis Resource (HHEAR). The consortium will work together to develop common protocols for evaluation of participants who are currently affected with early manifestations of CKDu and control participants, to define common strategies for biological sampling and environmental assessment, and to determine analytic strategies to best use the samples collected by the consortium. This FOA will not support intervention trials to prevent or treat CKDu. This FOA is intended to support only human studies and applications that include animal or model systems are not responsive.
Funding Opportunity RFA-DK-20-018 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites applications for a Renal Science Core to support and provide scientific guidance as part of the new consortium to study Chronic Kidney Disease of UnceRtain Etiology (CKDu) in Agricultural Communities (CURE). The Renal Analytic Core (RAC) will provide leadership in discovery science and support the analytic needs of the new consortium. The RAC will assess renal function, analyze kidney biopsies, devise and carry out a scientific approach to understanding the cause or causes of CKDu, including planning a biological sampling strategy to be implemented at Field Sites. This collaborative research consortium will bring together a broad range of expertise and enable discovery science to understand the cause or causes of CKDu and disease progression. The consortium will also work to identify potential therapeutic targets and public health interventions. The consortium will consist of a Scientific Data Coordinating Center, Field Sites, a Renal Analytic Core and the NIEHS Human Health Exposure Analysis Resource (HHEAR). The consortium will work together to develop common protocols for evaluation of participants who are currently affected with early manifestations of CKDu and control participants, to define common strategies for biosampling and environmental assessment, and to determine analytic strategies to best use the samples collected by the consortium. This FOA will not support intervention trials to prevent or treat CKDu. This FOA is intended to support only human studies and applications that include animal or model systems are not responsive.
Funding Opportunity RFA-DK-20-017 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites applications for Field Sites to enroll research participants in the consortium to study Chronic Kidney Disease of UnceRtain Etiology (CKDu) in Agricultural Communities (CURE). The Field Sites will identify, recruit and study participants with evidence of CKDu and appropriate controls, and collect biological and environmental samples. This collaborative research consortium will bring together a broad range of expertise and enable discovery science to understand the cause or causes of CKDu and disease progression. The consortium will also work to identify potential therapeutic targets and public health interventions. The consortium will consist of a Scientific Data Coordinating Center, Field Sites, a Renal Analytic Core and the NIEHS Human Health Exposure Analysis Resource (HHEAR). The consortium will work together to develop common protocols for evaluation of participants who are currently affected with early manifestations of CKDu and control participants, to define common strategies for biological sampling and environmental assessment, and to determine analytic strategies to best use the samples collected by the consortium. This FOA will not support intervention trials to prevent or treat CKDu. This FOA is intended to support only human studies and applications that include animal or model systems are not responsive.
Notice NOT-CA-20-086 from the NIH Guide for Grants and Contracts
Notice NOT-CA-20-091 from the NIH Guide for Grants and Contracts
Funding Opportunity RFA-RM-20-018 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) seeks applications for the development of an Open Data Science Platform and Coordinating Center as part of a broader initiative entitled Harnessing Data Science for Health Discovery and Innovation in Africa (DS-I Africa). The goal of DS-I Africa is to spur new health discoveries and catalyze innovation in healthcare, public health, and health research on the continent through application of data science. The FOA is comprised of two components the DS-I Africa Open Data Science Platform (ODSP) and Coordinating Center (CC) funded via one U2C award. The ODSP core will develop and maintain a scalable data-sharing gateway available to the research community with access to disparate types of open and controlled-access data and tools, generated from the DS-I Africa Research Hubs as well as other existing sources. The CC core will provide the organizational framework for the management, direction, and overall coordination of all common DS-I Africa consortium activities. The cooperative agreement will be awarded to an African academic or other non-profit institution. Multisectoral partnerships with other organizations in Africa, the U.S., or other countries are encouraged.
Funding Opportunity RFA-RM-20-017 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is to support research on the Ethical, Legal, and Social Implications (ELSI) associated with a new program entitled Harnessing Data Science for Health Discovery and Innovation in Africa (DS-I Africa). The goal of DS-I Africa is to spur new health discoveries and catalyze innovation in healthcare, public health, and health research on the continent through application of data science. A primary goal of this FOA is to explore the ELSI issues impacting data science for health research from an African perspective and contribute to the policy discussions of such on the continent. Through this FOA and related announcements, it is expected that ELSI research efforts will be fully embedded and integrated components of the consortia of activities supported through related DS-I Africa FOAs. Supported DS-I Africa ELSI awardees will work closely with DS-I Africa coordinating centers and DS-I Africa research hubs in considering how to dynamically address core ethical issues that may arise as the larger research projects uncover additional opportunities in this space. The cooperative agreements made through this FOA must be direct awards to African institutions, but applications can include partnerships with organizations from other areas.
Funding Opportunity RFA-RM-20-016 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) seeks applications for Research Training Programs as part of a broader initiative entitled Harnessing Data Science for Health Discovery and Innovation in Africa (DS-I Africa). The goal of DS-I Africa is to spur new health discoveries and catalyze innovation in healthcare, public health, and health research on the continent through application of data science. Through this FOA, DS-I Africa aims to increase capacity to carry out data science health research and innovation in Africa through the support of at least 4 institutional research training cooperative agreement awards. Applicants should propose long-term data science health research training through graduate degree (master's and/or doctoral) training and faculty development. Grantees will train cohorts of African investigators who will have the skills to become independent investigators, research leaders, and research collaborators. The cooperative agreements can either be direct awards to African institutions or awards to U.S. institutions in partnership with African institutions. Regardless of the applicant organization, the training programs must focus on building institutional capacity at one or more African institutions and train African researchers. Partnerships with additional organizations, including for-profit or governmental organizations, are encouraged as a means to provide applied research experiences for the trainees. This Funding Opportunity Announcement (FOA) allows appointment of Trainees proposing to serve as the lead investigator of an independent clinical trial; or proposing a separate ancillary clinical trial; or proposing to gain research experience in a clinical trial led by another investigator, as part of their research and career development.
Funding Opportunity RFA-RM-20-015 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) seeks applications for Research Hubs as part of a broader initiative entitled Harnessing Data Science for Health Discovery and Innovation in Africa (DS-I Africa). The goal of DS-I Africa is to spur new health discoveries and catalyze innovation in healthcare, public health, and health research on the continent through application of data science. DS-I Africa Research Hubs will be funded to advance data science health research and innovation in Africa and support new African and global partnerships that enhance the impact of data science health research. Hubs will engage government, industry, or other organizations, including diverse departments from academic institutions, that can partner to provide synergistic expertise, collaborate on research, and support data science linked to new technologies and solutions. Applicants must propose at least 2 distinct research projects and a system for soliciting, evaluating, and awarding smaller pilots projects, all focused on a central health theme that addresses priorities in an African country or region. Applications must be submitted from African academic or other non-profit organizations. Proposed partnerships with organizations outside the applicant institution are required and can include all types of organizations in Africa, the U.S., or other countries.
Funding Opportunity PAR-20-278 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites grant applications for the Outstanding Investigator Award (R35) in any area of cancer research. The objective of the National Cancer Institute (NCI) Outstanding Investigator Award (OIA) is to provide long-term support to accomplished investigators with outstanding records of cancer research productivity who propose to conduct exceptional research. The OIA is intended to allow investigators the opportunity to take greater risks, be more adventurous in their lines of inquiry, or take the time to develop new techniques. The OIA would allow an Institution to submit applications nominating established Program Directors/Principal Investigators (PDs/PIs) for the NCI OIA. It is expected that the OIA would provide extended funding stability and encourage investigators to embark on projects of unusual potential in cancer research. The research projects should break new ground or extend previous discoveries toward new directions or applications that may lead to a breakthrough that will advance biomedical, behavioral, or clinical cancer research.
Notice NOT-HS-20-013 from the NIH Guide for Grants and Contracts
Notice NOT-OD-20-148 from the NIH Guide for Grants and Contracts
Notice NOT-DK-20-036 from the NIH Guide for Grants and Contracts
Funding Opportunity PAR-20-281 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity (FOA) is to support research that explores the premise that fertility status can be a marker for overall health. Chronic conditions such as concer, diabetes, and obesity can impair fertility, however, less is known about the extent to which fertility status can impact or acts as a marker for overall health. Data suggest that infertility is not necessarily a unique disease of the reproductive axis but is often physiologically or genetically linked with other diseases and conditions. Recent epidemiologic studies demonstrate links between fertility status in both males and females and various somatic diseases and disorders. Taken together, these data strongly suggest that fertility status can be a window into overall health. Advancing this premise will require substantive involvement of experts in reproductive health/fertility along with expert in another non-reproductive specialty appropriate to the area of overall health being investigated, for example, in other fields such as epidemiology, or the somatic disease in question. This FOA focuses on studies evaluating fertility as a marker for overall health, and therefore applications that look at the effects of the disease or disorder on fertility are outside of the scope of this program. Recruitment of new cohorts will not be supported by this FOA.
Funding Opportunity PAR-20-282 from the NIH Guide for Grants and Contracts. T?he purpose of this funding opportunity announcement (FOA) is to support exploratory/developmental research that explores the premise that fertility status can be a marker for overall health. Chronic conditions such as cancer, diabetes, and obesity can impair fertility, however, less is known about the extent to which fertility status can impact or act as a marker for overall health. Data suggest that infertility is not necessarily a unique disease of the reproductive axis but is often physiologically or genetically linked with other diseases and conditions. Recent epidemiologic studies demonstrate links between fertility status in both males and females and various somatic diseases and disorders. Taken together, these data strongly suggest that fertility status can be a window into overall health. Advancing this premise will require substantive involvement of experts in reproductive health/fertility along with expert in another non-reproductive specialty appropriate to the area of overall health being investigated, for example, experts in other fields such as epidemiology, or the somatic disease in question,. This FOA focuses on studies evaluating fertility as a marker for overall health, and therefore applications that look at the effects of a disease or disorder on fertility are outside of the scope of this program. Recruitment of new cohorts will not be supported by this FOA.
Funding Opportunity RFA-AG-21-028 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) is a limited competition FOA inviting cooperative agreement (U01) applications from investigators currently participating in the Look AHEAD (Action for Health in Diabetes) Consortium. The purpose of this limited competition will be to allow an additional 5-year follow-up period of all currently enrolled participants. The goals of the Action for Health in Diabetes Extension (Look AHEAD-E) study are to examine the long-term effects of an intensive lifestyle intervention designed to produce weight loss on health, function, and healthcare utilization.
Notice NOT-CA-20-088 from the NIH Guide for Grants and Contracts