NIH Weekly Funding Opportunities and Policy Notices
Notice NOT-OD-25-002 from the NIH Guide for Grants and Contracts
Notice NOT-AA-24-016 from the NIH Guide for Grants and Contracts
Notice NOT-OD-25-001 from the NIH Guide for Grants and Contracts
Notice NOT-DE-25-041 from the NIH Guide for Grants and Contracts
Funding Opportunity RFA-AG-25-008 from the NIH Guide for Grants and Contracts. This NOFO invites applications for a Demography and Economics of Aging and AD/ADRD Coordinating Center (D and E CC) whose purpose is to act as a hub, serving the needs of theCenters on the Demography and Economics of Aging, including Alzheimer's Disease and Alzheimer's Disease-Related Dementias (AD/ADRD) (D and E Centers)as well as the needs of National Institute on Aging program staff. The D and E Centers Program focuses on advancing aging research indemography, economics, and related interdisciplinary population-based social science areas, including those with a focus on Alzheimer's disease and Alzheimer's disease-related dementias (AD/ADRD).The CC will be a bridge among D and E Centers, institutions, individual scholars, the NIA, and the research and policy communities. The CC will enhance the scientific impact of the D and E Centers Programs and foster synergies across D and E Centers, other NIA-funded P30 Centers Programs, and NIA-funded research infrastructure (e.g., longitudinal datasets, contextual data repositories, etc.) as well as promote inclusion and representation across a diverse group of scholars and institutions, including via shared mentorship and training activities. The D and E CC will also build and execute approaches to raise the profile of the D and E Centers Programs and the demography and economics of aging, including AD/ADRD.
Funding Opportunity RFA-AG-25-007 from the NIH Guide for Grants and Contracts. The purpose of this Notice of Funding Opportunity (NOFO) is to invite applications to develop or renew a Research and Development Center (P30) to advanceaging research indemography, economics, and related interdisciplinary population-based social science areas, including those with a focus on Alzheimer's disease and Alzheimer's disease-related dementias (AD/ADRD). The objectives of the Demography and Economics of Aging (D and E Centers) (P30) Program are to: 1) Seed new and innovative lines of aging research in demography, economics, and related interdisciplinary population-based social science areas. 2) Integrate approaches that address the disproportionate distribution of health within and/oracross populations, including with respect to those defined as Health Disparity Priority Populations in theNIA Health Disparities Research Framework. 3) Incorporate strategies that will identify and engage scholars across disciplines, career stages, and institutions. D and E Centers shall support the infrastructure and pilot data necessary for research and program development in Center-identified population-based social science aging research themes by investigators within an institution and/or across domestic institutions.
Funding Opportunity RFA-AI-24-067 from the NIH Guide for Grants and Contracts. The purpose of this Notice of Funding Opportunity (NOFO) is to support early to mid-stage research focused on development of alternative human models of acute and/or delayed radiation-induced injuries (extracorporeal systems) to elucidate mechanisms of injury and to test medical countermeasures to treat and/or mitigate these injuries.
Funding Opportunity PAR-24-305 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity (NOFO) invites U54 cooperative agreement applications for the support and advancement of the Centers for Precision Disease Modeling. The goal of the Centers is to support collaborative research projects that bridge current personalized medicine efforts in human subjects with advances in animal genomics and genetic manipulation technologies, including the creation of interspecies somatic hybrids. By functionally linking these areas of research, the Centers aim to enhance the predictive value of preclinical studies through the use of precision animal models. Each Center will develop a process by which the research community can nominate unique human genomic variants for cost effective high-throughput testing in an animal model pipeline. After validation of the expected gene editing, the Centers will support assays to conduct comprehensive functional and phenotyping analyses to evaluate disease-causing variants. A key mission of the Centers is the creation and distribution of precision animal model resources and related services to the biomedical community. Therefore, Centers will establish pipelines for preclinical scientific discovery, disease modeling, and development of interventions based on innovative animal models. While the Centers will focus on a limited number of targeted projects, they are expected to develop and maintain multifaceted research activities that can be adjusted to accommodate a wide range of diseases.
Funding Opportunity PA-25-093 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity (NOFO) intends to support fundamental research that will contribute to basic understanding of skin injuries caused by chemicals that have been identified as public health threats, with an emphasis on investigating the commonalities of such injuries and identifying potential shared signaling pathways and therapeutic targets for medical countermeasure development.
Notice NOT-AA-24-012 from the NIH Guide for Grants and Contracts
Notice NOT-EB-24-014 from the NIH Guide for Grants and Contracts
Notice NOT-HS-25-001 from the NIH Guide for Grants and Contracts
Notice NOT-HL-24-033 from the NIH Guide for Grants and Contracts
Notice NOT-CA-25-005 from the NIH Guide for Grants and Contracts
Funding Opportunity RFA-CA-25-010 from the NIH Guide for Grants and Contracts. This notice of funding opportunity (NOFO) invites proposals for Research Projects to advance the science of scale-up and sustainment of tobacco use treatment (TUT) for cancer survivors. Each Research Project will propose a trial to test implementation strategies to equitably and effectively scale-up and sustain the delivery of TUT to a large number of diverse clinical care delivery settings and cancer survivor populations, with an emphasis on cancer survivor populations experiencing health inequities.
Notice NOT-DE-25-040 from the NIH Guide for Grants and Contracts
Notice NOT-OD-25-004 from the NIH Guide for Grants and Contracts
Notice NOT-GM-25-001 from the NIH Guide for Grants and Contracts
Notice NOT-HS-24-027 from the NIH Guide for Grants and Contracts
Funding Opportunity PAR-25-050 from the NIH Guide for Grants and Contracts. The purpose of this notice of funding opportunity (NOFO) is to support rigorous analytical validation of method(s) used for measuring biomarkers for neurological and neuromuscular disorders for use in clinical trials or clinical practice. Applicants must justify the unmet need for the biomarker(s) and measurement methods and specify one or two context(s) of use for the biomarker(s). Activities supported include optimizing and evaluating the accuracy, precision, reportable range, and analytical sensitivity and specificity of the detection method across multiple sites and operators and establishing reference intervals and quality control procedures. Multi-site applications are expected but not required.