NIH Weekly Funding Opportunities and Policy Notices
Funding Opportunity PA-17-061 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is to encourage exploratory/developmental research grant applications to: (1) assess and describe the current state of oral anticancer medication utilization, delivery, and adherence; (2) identify structural, systemic, and psychosocial barriers to adherence; and (3) develop models and strategies to improve safe and effective delivery of these agents so that clinical outcomes are optimized. Applications should focus research questions on at least one of the following: specific cancer type; class of drugs; and/or groups subject to disparities (e.g., elderly populations, members of low socioeconomic groups, racial/ethnic minorities). Research may be focused at the patient (pediatric, adolescent, or adult), patient-caregiver, provider, health care team, or health care delivery system level, and may include intervention studies, observational studies, or mixed-methods studies. Observational studies should emphasize modifiable risk factors for future intervention research.
Funding Opportunity RFA-AI-16-078 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) solicits applications from currently funded Program Directors/Principal Investigators, Mechanistic Subcommittee members, core laboratory leaders and clinical site leaders in the "Clinical Trials in Organ Transplantation in Children (CTOT-C)" Program to support the conduct of studies of immune mechanisms using samples and clinical data collected from pediatric solid organ transplant recipients obtained in (a) ongoing or completed CTOT-C clinical studies, or (b) from other clinical trials in which the samples and data were collected with a demonstrably similar level of investigational rigor. Research supported under this FOA will focus on understanding graft dysfunction and/or loss and immune-mediated morbidity and mortality in pediatric transplant recipients. This FOA will leverage the samples and data gathered from CTOT-C's unique cohort of well-characterized patients, as well as the consortium infrastructure to carry out timely hypothesis-driven mechanistic studies. Successful ancillary mechanistic investigations will enhance the value of ongoing and completed CTOT-C projects, improve the research community's understanding of pediatric transplantation, and contribute to the identification of novel and robust surrogate endpoints for future interventional trials and/or novel therapeutic targets and biomarkers for diagnosis, treatment, and disease monitoring.
Funding Opportunity RFA-OD-17-001 from the NIH Guide for Grants and Contracts. The purpose of this FOA is for the support of a Research Resource for Human Organs and Tissues for the continued availability of human tissues and organs to biomedical researchers in the United States. The research resource is expected to facilitate procurement, preservation, and distribution of human tissues and organs to qualified biomedical researchers.
Funding Opportunity RFA-CA-16-501 from the NIH Guide for Grants and Contracts. The purpose of this limited Funding Opportunity Announcement (FOA) is to support the infrastructure to design and conduct multi-institutional Phase I and early Phase II clinical immunotherapy trials for cancer patients, using novel immunomodulatory agents. To realize these goals, the FOA will continue to support the research activities of the Cancer Immunotherapy Trials Network (CITN).
Funding Opportunity PAR-17-059 from the NIH Guide for Grants and Contracts. The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching goal of this National Cancer Institute (NCI) R25 program is to support educational activities that enhance the diversity of the biomedical, behavioral and clinical research workforce.
Funding Opportunity PA-17-062 from the NIH Guide for Grants and Contracts. The purpose of this initiative is to stimulate research in promoting caregiver health using self-management. Caregiving is an important science area since the number of people living longer with chronic conditions is growing. Informal caregivers (lay caregivers) are defined as unpaid individuals (spouses, partners, family members, friends, or neighbors) involved in assisting others with activities of daily living and/or medical tasks. Formal caregivers are paid, delivering care in ones home or care settings (daycare, residential care facility). This concept focuses on informal caregivers.
Notice NOT-MH-17-006 from the NIH Guide for Grants and Contracts
Notice NOT-HL-16-476 from the NIH Guide for Grants and Contracts
Notice NOT-HS-17-004 from the NIH Guide for Grants and Contracts
Notice NOT-AG-16-082 from the NIH Guide for Grants and Contracts
Notice NOT-DE-17-003 from the NIH Guide for Grants and Contracts
Notice NOT-CA-17-005 from the NIH Guide for Grants and Contracts
Notice NOT-DE-17-004 from the NIH Guide for Grants and Contracts
Notice NOT-OD-17-022 from the NIH Guide for Grants and Contracts
Notice NOT-HL-16-472 from the NIH Guide for Grants and Contracts
Notice NOT-HL-16-471 from the NIH Guide for Grants and Contracts
Notice NOT-DK-17-002 from the NIH Guide for Grants and Contracts
Funding Opportunity RFA-RM-16-018 from the NIH Guide for Grants and Contracts. The purpose of this FOA is to solicit applications for continuation of a Coordinating Center to provide national leadership for the NIH Health Care Systems (HCS) Research Collaboratory program. The Coordinating Center will 1) further develop, adapt, and adopt technical and policy guidelines and best practices for the effective conduct of research studies in partnership with health care systems; 2) work collaboratively with each Demonstration Project team supported through the Collaboratory program, including their partnering health care systems, to develop, test, and implement the proposed Demonstration Projects while providing technical, design, and coordination support; 3) learn and disseminate the best strategies for engaging health care systems as research partners to improve health and care delivery; and 4) learn, develop, and disseminate the best means of conducting pragmatic clinical trials in health care systems to improve the scientific communitys ability to perform future pragmatic trials. The Coordinating Center will also serve as the central resource for the activities of the HCS Collaboratory.
Funding Opportunity RFA-RM-16-019 from the NIH Guide for Grants and Contracts. The purpose of this FOA is to solicit applications to support Demonstration Projects that include an efficient, large-scale pragmatic clinical trial. Trials must be conducted across two or more health care systems (HCS) and must be conducted as part of the NIH HCS Research Collaboratory supported through the NIH Common Fund. (See https://commonfund.nih.gov/hcscollaboratory). Awards made through this FOA will initially support a one-year milestone-driven planning phase (UG3), with possible rapid transition to the second implementation phase (UH3) for a pragmatic trial Demonstration Project. UH3s will be awarded after administrative review of eligible UG3s that have met the scientific milestone and feasibility requirements necessary for the UH3 implementation phase, depending on the availability of funds. The UG3/UH3 application must be submitted as a single application, and applicants should note specific instructions for each phase in this FOA.
Notice NOT-NS-17-009 from the NIH Guide for Grants and Contracts