NIH Weekly Funding Opportunities and Policy Notices
Notice NOT-EY-23-009 from the NIH Guide for Grants and Contracts
Notice NOT-OD-23-168 from the NIH Guide for Grants and Contracts
Notice NOT-AG-23-051 from the NIH Guide for Grants and Contracts
Notice NOT-HL-23-115 from the NIH Guide for Grants and Contracts
Notice NOT-HL-23-114 from the NIH Guide for Grants and Contracts
Notice NOT-NS-23-107 from the NIH Guide for Grants and Contracts
Funding Opportunity RFA-NS-24-023 from the NIH Guide for Grants and Contracts. To enable the development and validation of real-world remote digital endpoints from wearable devices for monitoring pain experience and progression, response to interventions, and impact on quality of life. In the context of this RFA, endpoints will include biosignatures derived from functional and physiological assessments detected from wearable devices. These biosignatures can be used to monitor the effects of therapeutics developed for the treatment of pain.
Notice NOT-EB-23-018 from the NIH Guide for Grants and Contracts
Funding Opportunity RFA-NR-24-001 from the NIH Guide for Grants and Contracts. The purpose of this initiative is to advance research that reduces firearm injury and disparities through the development and evaluation of firearm injury primary prevention interventions leveraging community healthcare settings.
Notice NOT-NS-24-012 from the NIH Guide for Grants and Contracts
Funding Opportunity RFA-MH-24-190 from the NIH Guide for Grants and Contracts. Reissue of RFA-MH-21-205 to comply with DMS Policy. This Notice of Funding Opportunity (NOFO), in support of the NIH Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative, is one of several NOFOs aimed at supporting transformative discoveries that will lead to breakthroughs in understanding human brain function. Guided by the long-term scientific plan, BRAIN 2025: A Scientific Vision, this NOFO specifically seeks to support efforts addressing core ethical issues associated with research focused on the human brain and resulting from emerging technologies and advancements supported by the BRAIN Initiative. The hope is that efforts supported under this NOFO might be both complementary and integrative with the transformative, breakthrough neuroscience discoveries supported through the BRAIN Initiative.
Funding Opportunity RFA-MH-25-125 from the NIH Guide for Grants and Contracts. The purpose of this R34 NOFO is to provide resources for evaluating the feasibility, acceptability, and safety of novel approaches that are uniquely tailored to the risk profiles of these populations, that will improve outcomes and modify health risk behavior. Resources may also be used for obtaining the preliminary data needed as a prerequisite to a larger-scale (efficacy or effectiveness) services study. The goal is to support research that develops and tests broadly implementable service system interventions to rapidly identify and effectively respond to reduce suicide and suicidal behavior in various groups of at-risk youth. Specifically, the goals of this NOFO are to: 1) develop a multi-level service system intervention that coordinates suicide risk identification, evaluation, and linkage to needed treatment and services for a specifically identified at-risk youth group; 2) test the feasibility and effectiveness of the intervention in detecting and reducing suicide risk and suicidal behavior in the at-risk youth group; and 3) demonstrate the intervention's implementation and potential for future uptake in underserved, under-resourced community settings where additional at-risk youth are most likely to receive care. The ultimate goal of this NOFO is to develop and test the effectiveness of evidence-based strategies for detecting and preventing suicide and suicidal behavior among at-risk youth. It focuses on systems interventions to improve outcomes for youth and is not intended to support the development of new screening tools or assessment instruments.
Funding Opportunity RFA-MH-25-126 from the NIH Guide for Grants and Contracts. The purpose of this R01 NOFO is to provide resources for evaluating the feasibility, acceptability, and safety of novel approaches that are uniquely tailored to the risk profiles of these populations, that will improve outcomes and modify health risk behavior. Resources may also be used for obtaining the preliminary data needed as a prerequisite to a larger-scale (efficacy or effectiveness) services study. The goal of the R01 NOFO is to support research that develops and tests broadly implementable service system interventions to rapidly identify and effectively respond to reduce suicide and suicidal behavior in various groups of at-risk youth. Specifically, the goals of this NOFO are to: 1) develop a multi-level service system intervention that coordinates suicide risk identification, evaluation, and linkage to needed treatment and services for a specifically identified at-risk youth group; 2) test the feasibility and effectiveness of the intervention in detecting and reducing suicide risk and suicidal behavior in the at-risk youth group; and 3) demonstrate the intervention's implementation and potential for future uptake in underserved, under-resourced community settings where additional at-risk youth are most likely to receive care. The ultimate goal of this NOFO is to develop and test the effectiveness of evidence-based strategies for detecting and preventing suicide and suicidal behavior among at-risk youth. It focuses on systems interventions to improve outcomes for youth and is not intended to support the development of new screening tools or assessment instruments.
Notice NOT-HL-23-109 from the NIH Guide for Grants and Contracts
Funding Opportunity PAR-23-289 from the NIH Guide for Grants and Contracts. The purpose of this Notice of Funding Opportunity is to solicit applications for clinical sites that will provide expert diagnostic services for undiagnosed diseases across the nation. The clinical sites known as Diagnostic Centers of Excellence (DCoEs) will partner with the Undiagnosed Diseases Network (UDN) to sustain some of the key research activities currently performed by the Phase II UDN Clinical sites (see:RFA-RM-17-019) and facilitate its transition to a larger network that serves diverse undiagnosed patient populations. The DCoEs will establish collaborations and efficient processes with the Data Management and Coordinating Center (DMCC; see: RFA-NS-22-051); enroll and evaluate new participants; and foster scientific discovery. This NOFO requires a Plan for Enhancing Diverse Perspectives (PEDP), which will be assessed as part of the scientific and technical peer review evaluation. Applications that fail to include a PEDP will be considered incomplete and will be withdrawn. Applicants are strongly encouraged to read the FOA instructions carefully and view the available PEDP guidance material.
Funding Opportunity RFA-AI-23-055 from the NIH Guide for Grants and Contracts. The purpose of this Notice of Funding Opportunity (NOFO) is to support high risk, milestone-driven approaches for the development of robust culture techniques, and/or genetic and molecular tools to better understand the biology of select human eukaryotic pathogens including the microsporidian Enterocytozoon bieneusi; Pneumocystis jirovecii; Plasmodium vivax; and Babesia microti. This NOFO will use a milestone-driven, biphasic award mechanism. Transition to the second phase will depend on the successful completion of milestones.
Notice NOT-OD-23-169 from the NIH Guide for Grants and Contracts
Notice NOT-NS-23-109 from the NIH Guide for Grants and Contracts
Funding Opportunity PAR-23-237 from the NIH Guide for Grants and Contracts. The purpose of this Notice of Funding Opportunity (NOFO) is to support established biomedical data resources, that have demonstrated impact and have potential for continued benefit to the mission of one or more of the NIH Institutes and Centers participating in this announcement. Each application must: (a) deliver scientific impact to the communities served; (b) employ and promote good data management practices (as outlined by the FAIR Data Principles including adherence to the NIH desirable characteristics of repositories) and efficient operations for quality and services; (c) engage with the user community and continuously address their needs; and (d) support a process for data life-cycle analysis, long-term preservation, and trustworthy governance. The evaluation of the repositories will be based on their usage, utility, impact, quality of data and services, and efficiency of operations, community needs and engagement, trustworthiness of stewardship, and governance.
Funding Opportunity PAR-23-236 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) supports the development of early-stage or new data repositories and knowledgebases as distinct and separate resources that could be valuable for the biomedical research community.