NIH Weekly Funding Opportunities and Policy Notices
Funding Opportunity PAR-23-209 from the NIH Guide for Grants and Contracts. The NEI uses UG1 cooperative agreement awards to support investigator-initiated large-scale clinical trials, human gene-transfer, stem cell therapy trials, and other complex or high resource- or safety-risk clinical trials. These projects are multifaceted and of high public health significance requiring clear delineation of study organization including roles and responsibilities and require careful performance oversight and monitoring. For purposes of this Notice of Funding Opportunity (NOFO), the proposed study must be intended to evaluate interventions aimed at screening, diagnosing, preventing, or treating vision disorders, or to compare the effectiveness of two or more established interventions. The NEI UG1-supported studies are typically funded as a group of single-component companion grant awards including the Chairs Grant, the Coordinating Center, and Resource Centers, when appropriate. Specifically, this NOFO encourages applications for the Chair's grant, which includes the scientific rationale, study aims and significance of the research project.
Notice NOT-OD-23-132 from the NIH Guide for Grants and Contracts
Notice NOT-HL-23-083 from the NIH Guide for Grants and Contracts
Notice NOT-CA-23-064 from the NIH Guide for Grants and Contracts
Funding Opportunity PAR-23-182 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity (NOFO) invites applications to support research projects focused on the expansion of existing or development of new ontologies for behavioral or social science research (BSSR). The research projects must include multi-disciplinary teams of subject matter experts in one or more BSSR fields, as well as ontology related informatics and computational approaches. Projects should address health-related behavioral and social science problems not easily solved without improvement in semantic knowledge structures (e.g., controlled vocabularies, taxonomies, and ontologies). Each project should identify one or more BSSR use cases and elucidate how the proposed ontological resources or tools to be developed and tested will advance BSSR research capabilities and efficiencies. This includes a plan for promoting dissemination and use of the resources and tools. Tools or resources proposed should include health-relevant terminology related to constructs, measures, and/or intervention components. Tools or resources must also account for socio-behavioral cultural context in vocabulary/ontology development. As part of a cooperative agreement, each project will focus on independent ontology development research aims and be expected to work collaboratively with the Dissemination and Coordination Center (DCC; PAR-23-181) and the other funded projects in a Behavioral and Social Science Ontology Development U01 Research Network.
Funding Opportunity PAR-23-181 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity (NOFO) invites applications from multi-disciplinary teams to establish a Dissemination and Coordination Center (DCC) for the Behavioral and Social Science Ontology Development U01 Research Network Projects (PAR-23-182). Teams must include subject matter experts in 1) one or more fields of behavioral or social science, 2) ontology-related informatics and computational approaches, and 3) Team Science or the Science of Science. The primary responsibilities of the DCC are to: 1) Coordinate and provide logistical support to facilitate collaboration and cross-project learning; 2) Provide ontology-related technical, computational, and informatics expertise and support; 3) Facilitate dissemination of resources and training to support ontology expansion, development, and use; and 4) Provide active outreach and coordination with relevant stakeholders to increase understanding of and demand for BSSR ontology-related tools and resources.
Notice NOT-AG-23-025 from the NIH Guide for Grants and Contracts
Notice NOT-HL-23-088 from the NIH Guide for Grants and Contracts
Notice NOT-AA-23-008 from the NIH Guide for Grants and Contracts
Notice NOT-HD-23-016 from the NIH Guide for Grants and Contracts
Notice NOT-HD-23-015 from the NIH Guide for Grants and Contracts
Funding Opportunity RFA-AA-23-002 from the NIH Guide for Grants and Contracts. This FOA uses the NIH Comprehensive Research Center (P60) mechanism to support an integrated, broad-based multidisciplinary, multi-investigator, long-term program of research and research support activities planned around a specific major research theme.
Funding Opportunity RFA-AA-23-001 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity (NOFO) invites applications for specialized Alcohol Research Centers using the P50 mechanism. The overall purpose of the NIAAA Alcohol Research Center program is to provide leadership in conducting and fostering interdisciplinary, collaborative research on a wide variety of topics relevant to the Institutes mission. These topics include, but are not limited to: the nature, etiology, genetics, diagnosis, treatment, and prevention of alcohol use disorder, alcohol-related end organ diseases and their biomedical, psychosocial, and economic consequences across the lifespan and racial/ethnic groups and other health disparity populations. Centers also are regional or national resources that contribute to the development of new research methods, technologies and approaches that sustain innovative goal-directed research.
Funding Opportunity PAR-23-212 from the NIH Guide for Grants and Contracts. This FOA would support establishing deeper mechanistic insight and causal relationships between TDP-43 pathology and phenotypic outcomes, as well as mechanistic interactions between TDP-43 and other co-pathologies, such TMEM106B. Additionally, it would include comparisons (including mechanistic, molecular, structural, cellular, genetic, -omic, anatomical, neuropathological, etc.) between TDP-43 proteinopathies, including LATE, with or without AD-NC, and FTD and/or ALS.
Funding Opportunity PAR-23-211 from the NIH Guide for Grants and Contracts. This FOA would support investigations with a minimum of two relevant co-pathologies (e.g., tau, alpha-synuclein, TDP-43, TMEM106B, vascular), with optional risk factors and co-morbidities, to identify cellular and molecular mechanisms of how/why multi-proteinopathy interactions drive worsening neurodegenerative processes and phenotypic outcomes. Studies should examine co-pathology cellular and molecular interactions across brain regions and time in proximate cell population, across various intracellular dynamics and localization, and upstream and downstream from aggregated protein states to determine what events lead to worse phenotypic outcomes.
Funding Opportunity RFA-MD-23-011 from the NIH Guide for Grants and Contracts. The purpose of this NOFO is to further advance NIMHDs mission by supporting Centers of Excellence to enhance research training and education of academic faculty (including post-doctoral fellows, junior faculty, and other early-stage investigators) in the conduct of minority health and health disparities research.
Funding Opportunity RFA-DA-24-018 from the NIH Guide for Grants and Contracts. The FOA intends to spur the development of cost-effective technologies that may reduce or even eliminate disparities in SUD treatment. Disparities due to geographical access or rural/urban divide, due to treatment cost, or due to stigma will be specifically targeted. The intention is to bring to the treatment to the patient, not the patient to the treatment.
Funding Opportunity RFA-DA-24-017 from the NIH Guide for Grants and Contracts. The FOA intends to spur the development of cost-effective technologies that may reduce or even eliminate disparities in SUD treatment. Disparities due to geographical access or rural/urban divide, due to treatment cost, or due to stigma will be specifically targeted. The intention is to bring to the treatment to the patient, not the patient to the treatment.
Notice NOT-NS-23-086 from the NIH Guide for Grants and Contracts
Funding Opportunity RFA-DK-22-510 from the NIH Guide for Grants and Contracts. The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The overarching goal of this R25 program is to support educational activities that encourage individuals from diverse backgrounds, including those from groups underrepresented in the biomedical and behavioral sciences, to pursue further studies or careers in research.