Shoukat Dedhar, PhD
Distinguished Scientist, Genetics Unit,
Integrative Oncology
BC Cancer Research Centre
Professor Biochemistry and Molecular Biology,
University of British Columbia
Key discoveries have been the identification of Integrin-mediated signaling pathways leading to regulation of cell proliferation, survival and migration. The discovery of Integrin-Linked Kinase (ILK) in 1996 in the Dedhar laboratory has demonstrated how integrin receptors on different types of cells coordinate signals to regulate cellular homeostasis. ILK is required for embryonic development, for the formation of blood vessels and for cardiac function. It is also essential for the regulation of the proper development of neurons as well as the function of other cell types such as chondrocytes, smooth muscle cells, skin cells and hair follicle cells. Recent work using sophisticated Proteomics technology has revealed that ILK localizes to the centrosome, in addition of focal adhesions where integrins are present.”
WEDNESDAY MARCH 1ST, 2017
10:00 – 11:00AM
UA CANCER CENTER, ROOM 2920
Host: Anne E. Cress, PhD
The University of Arizona, College of Medicine – Tucson
Department of Cellular and Molecular Medicine